Drug | Tablet
Glimepiride 0.5 mg + Metformin Hydrochloride 500 mg (as sustained/extended release in some packs; check pack label)
Type 2 diabetes mellitus in adults when diet and exercise alone are not enough; helps control high blood sugar
Glimepiride (a sulfonylurea) increases insulin release from the pancreas. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity, lowering blood glucose levels.
Oral tablet; take exactly as prescribed. Usually taken once daily with food (often with breakfast) to reduce stomach upset and risk of low sugar. Swallow whole with water; do not crush/chew if it is SR/ER.
Common side effects of Glycomet GP 0.5 Tablet may include:
May cause hypoglycaemia—risk increases with missed meals, excess exercise, alcohol, or with other antidiabetics; carry glucose. Metformin rarely may cause lactic acidosis—risk higher with kidney disease, dehydration, severe infection, heart/respiratory failure, heavy alcohol use; stop and seek care for rapid breathing, severe weakness, muscle pain, unusual sleepiness. Avoid in severe renal impairment; kidney function should be checked before and during therapy. Temporarily stop metformin around iodinated contrast studies and major surgery as advised. Use caution in elderly and in liver disease; monitor blood glucose and HbA1c regularly.
