Amlopin M

Amlodipine (5mg) + Metoprolol Succinate (23.75mg)

Treatment of hypertension (high blood pressure); prevention/management of angina (chest pain) in patients requiring combination therapy

Amlodipine is a calcium channel blocker that relaxes blood vessels, lowering blood pressure and improving blood flow. Metoprolol is a cardioselective beta-blocker that slows heart rate and reduces the force of contraction, decreasing cardiac workload and blood pressure.

Take by mouth as advised by the physician, usually once daily. Swallow the tablet whole (do not crush/chew as it may be extended-release). Can be taken with or without food; take at the same time each day.

headache,dizziness,ankle swelling (edema),flushing,fatigue,slow heart rate (bradycardia),low blood pressure,cold extremities,nausea,constipation

Do not stop metoprolol suddenly (may worsen angina or cause rebound hypertension). Use with caution in asthma/COPD, diabetes (may mask hypoglycemia symptoms), heart block, bradycardia, heart failure, liver disease, and in the elderly. Monitor blood pressure and pulse regularly; rise slowly from sitting/lying to reduce dizziness. Seek urgent care for severe dizziness/fainting, very slow pulse, breathing difficulty, or swelling of face/lips.

Other antihypertensives (additive hypotension),verapamil/diltiazem (risk of bradycardia/heart block),digoxin (bradycardia),antiarrhythmics like amiodarone (conduction issues),CYP3A4 inhibitors/inducers affecting amlodipine (e.g., clarithromycin, azoles, rifampicin),NSAIDs (may reduce BP control),clonidine (withdrawal interaction),insulin/oral antidiabetics (mask hypoglycemia),alcohol (increases dizziness)

Store at room temperature (below 25°C), protected from moisture and light. Keep in original blister pack and out of reach of children.

Amlodipine+Metoprolol succinate tablets (generic),Amlodipine+Metoprolol ER combination tablets (other brands)