Glycomet Trio 0.5 Tablet

Composition of Glycomet Trio 0.5 Tablet

Glycomet Trio 0.5 Tablet contains Glimepiride 0.5 mg + Metformin Hydrochloride 500 mg (sustained release) + Voglibose 0.2 mg. It belongs to the Sulfonylurea + Biguanide + Alpha-glucosidase inhibitor class of medicines.

Uses of Glycomet Trio 0.5 Tablet

Type 2 diabetes mellitus in adults when blood glucose is not adequately controlled with diet/exercise and/or dual therapy; helps control fasting and post-meal blood sugar

Key benefits

• Controls fasting and post-meal blood sugar
• Improves insulin sensitivity and reduces hepatic glucose output
• Reduces carbohydrate absorption and post-meal spikes
• Helps lower HbA1c when dual therapy is insufficient

How Glycomet Trio 0.5 Tablet works

Metformin reduces glucose production in the liver and improves insulin sensitivity. Glimepiride stimulates the pancreas to release insulin. Voglibose slows carbohydrate digestion/absorption in the intestine, reducing post-meal blood sugar spikes.

How to take Glycomet Trio 0.5 Tablet

Tablet (oral). Take exactly as prescribed, usually once daily with/after meals (often with the first main meal) to reduce stomach upset and hypoglycaemia. Swallow whole with water; do not crush/chew sustained-release tablets. Follow diet and exercise advice and monitor blood glucose regularly.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. It may cause low blood sugar and marked stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glycomet Trio 0.5 Tablet

Most side effects of Glycomet Trio are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia
• nausea
• vomiting
• diarrhoea
• abdominal pain
• loss of appetite
• flatulence
• headache
• dizziness
• metallic taste
• weight gain
• skin rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glycomet Trio 0.5 Tablet

Warnings and precautions

Prescription-only (Schedule H). Risk of hypoglycaemia (higher with missed meals, alcohol, heavy exercise, elderly, kidney/liver impairment); carry sugar/glucose. Metformin may rarely cause lactic acidosis—seek urgent help for rapid breathing, severe weakness, abdominal pain, unusual drowsiness. Use with caution/avoid in severe renal impairment, severe liver disease, severe infection/dehydration, heart/respiratory failure, or alcoholism. Temporarily stop metformin around iodinated contrast studies and major surgery as advised by doctor. Monitor renal function, HbA1c, and vitamin B12 periodically. Not for type 1 diabetes or diabetic ketoacidosis.

Do not take Glycomet Trio if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis. Not for people with heart failure, active bladder cancer or unexplained blood in the urine.

Interactions with other medicines

Alcohol (increases hypoglycaemia/lactic acidosis risk), iodinated contrast media, insulin/other antidiabetics (additive hypoglycaemia), corticosteroids and diuretics (may raise glucose), beta-blockers (may mask hypoglycaemia symptoms), ACE inhibitors (may enhance glucose-lowering), fluoroquinolone antibiotics (glucose disturbances), cimetidine (may increase metformin levels), NSAIDs and other nephrotoxic drugs (increase renal risk)

How to store Glycomet Trio 0.5 Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Glycomet Trio 0.5 Tablet

Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them. Take it with the first mouthful of your meal so it can act on that meal. Expect some wind in the first weeks; it usually settles.

Manufacturer and class

Manufacturer:

USV LIMITED

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea + Biguanide + Alpha-glucosidase inhibitor