Prescription requiredAntidiabetic

Glycomet Trio 2 Tablet — Uses, Dosage & Benefits

Glycomet Trio 2 Tablet is used for Type 2 diabetes mellitus in adults when diet and exercise alone or dual therapy is inadequate; helps control blood sugar levels and improves glycaemic control..

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Buy Glycomet Trio 2 Tablet View full product details →

Active Ingredient / Composition

Glimepiride 2 mg + Metformin Hydrochloride (SR) 500 mg + Pioglitazone 15 mg

What is Glycomet Trio 2 Tablet used for?

Type 2 diabetes mellitus in adults when diet and exercise alone or dual therapy is inadequate; helps control blood sugar levels and improves glycaemic control.

How Glycomet Trio 2 Tablet Works

Glimepiride (a sulfonylurea) increases insulin release from the pancreas. Metformin reduces glucose production in the liver and improves insulin sensitivity. Pioglitazone (a thiazolidinedione) improves insulin sensitivity in muscle and fat by activating PPAR-γ, thereby reducing insulin resistance.

Dosage & Directions

Tablet (oral). Take exactly as prescribed by the doctor, usually once daily with/after the first main meal to reduce stomach upset and risk of low sugar. Swallow whole; do not crush/chew the SR tablet. Monitor blood glucose regularly and follow diet/exercise advice.

Always follow your doctor's prescription. Do not self-medicate.

Key Benefits

Lowers fasting and post-meal blood glucose
Improves insulin sensitivity and reduces insulin resistance
Helps achieve better HbA1c control than dual therapy
Convenient triple-drug regimen in one tablet
May reduce diabetes-related complications by improving glycaemic control

Pregnancy

Not recommended / Consult doctor (insulin is generally preferred in pregnancy).

Alcohol Interaction

Avoid

Glycomet Trio 2 Tablet — Quick Facts

Composition: Glimepiride 2 mg + Metformin Hydrochloride (SR) 500 mg + Pioglitazone 15 mg
Therapeutic class: Antidiabetic
Drug class: Sulfonylurea + Biguanide + Thiazolidinedione (PPAR-γ agonist) combination
Prescription: Required (Rx)
Price: ₹212
Habit forming: No
Storage: Store below 25°C in a cool, dry place. Protect from moisture and light. Keep in original blister pack and out of reach of children.

Glycomet Trio 2 Tablet — Usage FAQs

How should I take this medicine?

Follow the dosage prescribed by your doctor. Do not alter the dose without medical advice.

Can I take this medicine without a prescription?

Prescription-required medicines need a valid Rx. OTC medicines can be purchased directly.

What if I miss a dose?

Take the missed dose as soon as you remember, unless it is close to your next scheduled dose. Do not double the dose.

How long does it take to show effect?

The time to show effect varies by medicine and condition. Consult your doctor for specific timelines.

Glycomet Trio 2 Tablet — Uses, Dosage & Benefits

Active Ingredient / Composition

What is Glycomet Trio 2 Tablet used for?

How Glycomet Trio 2 Tablet Works

Dosage & Directions

Key Benefits

Pregnancy

Alcohol Interaction

Glycomet Trio 2 Tablet — Quick Facts

Glycomet Trio 2 Tablet — Usage FAQs

More from PingMeDoc™

Safety disclaimer

Glycomet Trio 2 Tablet — Uses, Dosage & Benefits

Active Ingredient / Composition

What is Glycomet Trio 2 Tablet used for?

How Glycomet Trio 2 Tablet Works

Dosage & Directions

Key Benefits

Pregnancy

Alcohol Interaction

Glycomet Trio 2 Tablet — Quick Facts

Glycomet Trio 2 Tablet — Usage FAQs

More from PingMeDoc™

Safety disclaimer