Prescription requiredHormonal therapy (Gynaecological)

Regestrone Tablet — Side Effects & Warnings

Known side effects of Regestrone Tablet include Nausea, headache, dizziness, breast tenderness, abdominal pain or bloating, spotting/breakthrough bleeding, change in menstrual flow, mood changes, weight gain, acne, fatigue. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

Common Side Effects

Nausea
headache
dizziness
breast tenderness
abdominal pain or bloating
spotting/breakthrough bleeding
change in menstrual flow
mood changes
weight gain
acne
fatigue

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Use only under medical supervision. Not recommended in pregnancy; rule out pregnancy before starting for amenorrhoea/bleeding. Caution/avoid in history of thromboembolism (DVT/PE), stroke, severe liver disease, liver tumors, unexplained vaginal bleeding, hormone-dependent cancers (e.g., breast/genital tract) unless directed by a specialist. May increase risk of blood clots; seek urgent care for leg swelling/pain, chest pain, shortness of breath, severe headache or vision changes. Use caution in diabetes, hypertension, migraine, depression, and smokers, especially >35 years.

Drug Interactions

Regestrone Tablet may interact with the following:

Enzyme inducers may reduce effect: rifampicin/rifabutin
phenytoin
carbamazepine
phenobarbital
primidone
topiramate
some antiretrovirals
St. John’s wort. May affect glucose tolerance (monitor with antidiabetics). Concomitant hormonal therapies may alter bleeding pattern/effect.

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Not recommended

Alcohol Interaction

Use with caution

Habit Forming

Storage

Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Regestrone Tablet — Safety Summary

Composition: Norethisterone (5mg)
Prescription: Required (Rx)
Pregnancy: Not recommended
Alcohol: Use with caution
Habit forming: No

Regestrone Tablet — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Full product details for Regestrone Tablet.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Regestrone Tablet — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026