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Sitaforce M 50/500 — Side Effects & Warnings

Known side effects of Sitaforce M 50/500 include Nausea, vomiting, diarrhoea, abdominal pain, loss of appetite, headache, dizziness, upper respiratory tract infection, nasopharyngitis. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Nausea
vomiting
diarrhoea
abdominal pain
loss of appetite
headache
dizziness
upper respiratory tract infection
nasopharyngitis

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Not for type 1 diabetes or diabetic ketoacidosis. Metformin can rarely cause lactic acidosis—risk increases with kidney impairment, dehydration, severe infection, heart failure, heavy alcohol use, or hypoxia; assess renal function before and during therapy. Stop temporarily before/after iodinated contrast or major surgery as advised. Sitagliptin may rarely cause pancreatitis, severe joint pain, allergic reactions, or bullous pemphigoid—seek care if severe abdominal pain or rash. Use caution in elderly and in hepatic impairment.

Drug Interactions

Sitaforce M 50/500 may interact with the following:

Alcohol (increases lactic acidosis risk)
iodinated contrast media
carbonic anhydrase inhibitors (e.g.
topiramate
acetazolamide)
cationic drugs affecting renal tubular secretion (e.g.
cimetidine)
diuretics
ACE inhibitors/ARBs
corticosteroids
thyroid hormones
sympathomimetics
oral contraceptives
other antidiabetics/insulin (increased hypoglycaemia risk)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.

Sitaforce M 50/500 — Safety Summary

Composition: Sitagliptin 50 mg + Metformin hydrochloride 500 mg
Prescription: Required (Rx)
Pregnancy: Consult doctor
Alcohol: Avoid
Habit forming: No

Sitaforce M 50/500 — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.