Prescription requiredHepatoprotective/Cholagogue (bile acid therapy)

Udirise SR 450 Tab 15S — Side Effects & Warnings

Known side effects of Udirise SR 450 Tab 15S include Diarrhoea, nausea, abdominal pain, indigestion, constipation, headache, dizziness, rash, itching. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Diarrhoea
nausea
abdominal pain
indigestion
constipation
headache
dizziness
rash
itching

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Use only on medical advice. Not suitable for calcified (radiopaque) gallstones, non-functioning gallbladder, acute cholecystitis/cholangitis, or biliary obstruction. Monitor liver function tests during therapy, especially in PBC/cholestasis. Use caution in severe liver disease; stop and consult doctor if persistent diarrhoea, severe abdominal pain, jaundice worsening, or allergic rash occurs.

Drug Interactions

Udirise SR 450 Tab 15S may interact with the following:

Bile acid sequestrants (cholestyramine
colestipol) and antacids containing aluminium/Smectite may reduce absorption (separate by 2–4 hours). Oestrogens/oral contraceptives and lipid-lowering agents like clofibrate may increase bile cholesterol and reduce effectiveness for gallstone dissolution. May alter levels/effects of ciclosporin; monitoring may be needed.

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor (use with caution; use only if clearly needed)

Alcohol Interaction

Use with caution (alcohol can worsen liver disease; follow doctor advice)

Habit Forming

Storage

Store below 25°C, in a dry place, protected from light and moisture. Keep out of reach of children.

Udirise SR 450 Tab 15S — Safety Summary

Composition: Ursodeoxycholic acid 450 mg (sustained release)
Prescription: Required (Rx)
Pregnancy: Consult doctor (use with caution; use only if clearly needed)
Alcohol: Use with caution (alcohol can worsen liver disease; follow doctor advice)
Habit forming: No

Udirise SR 450 Tab 15S — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.