Udirise SR 450 Tablet

Composition of Udirise SR 450 Tablet

Udirise SR 450 Tablet contains Ursodeoxycholic acid 450 mg (sustained release). It belongs to the Bile acid (ursodeoxycholic acid) class of medicines.

Uses of Udirise SR 450 Tablet

• Dissolution of cholesterol gallstones (in selected patients)
• primary biliary cholangitis (PBC)
• cholestatic liver diseases with impaired bile flow (as prescribed)

Key benefits

• Helps dissolve cholesterol gallstones
• Improves bile flow in cholestasis
• Protects liver cells from toxic bile acids
• Helps improve liver enzymes in PBC/other cholestatic disorders

How Udirise SR 450 Tablet works

Ursodeoxycholic acid is a hydrophilic bile acid that reduces cholesterol saturation in bile and helps dissolve cholesterol gallstones. It also improves bile flow and protects liver cells from toxic bile acids in cholestatic liver conditions.

How to take Udirise SR 450 Tablet

Take the tablet whole with water; do not crush or chew (SR formulation). Usually taken once daily or as directed by the physician, preferably after food/at bedtime. Duration is as advised; treatment for gallstones may take months.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause loose motions and stomach upset. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Udirise SR 450 Tablet

Most side effects of Udirise SR are mild and settle as the body adjusts. Reported side effects include:

• Diarrhoea
• nausea
• abdominal pain
• indigestion
• constipation
• headache
• dizziness
• rash
• itching

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Udirise SR 450 Tablet

Warnings and precautions

Use only on medical advice. Not suitable for calcified (radiopaque) gallstones, non-functioning gallbladder, acute cholecystitis/cholangitis, or biliary obstruction. Monitor liver function tests during therapy, especially in PBC/cholestasis. Use caution in severe liver disease; stop and consult doctor if persistent diarrhoea, severe abdominal pain, jaundice worsening, or allergic rash occurs.

Do not take Udirise SR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Bile acid sequestrants (cholestyramine, colestipol) and antacids containing aluminium/Smectite may reduce absorption (separate by 2–4 hours). Oestrogens/oral contraceptives and lipid-lowering agents like clofibrate may increase bile cholesterol and reduce effectiveness for gallstone dissolution. May alter levels/effects of ciclosporin; monitoring may be needed.

How to store Udirise SR 450 Tablet

Store below 25°C, in a dry place, protected from light and moisture. Keep out of reach of children.

Expert advice for Udirise SR 450 Tablet

Avoid alcohol entirely, and avoid unnecessary medicines and unregulated herbal preparations. Weight loss and exercise are the proven treatment for fatty liver.

Manufacturer and class

Manufacturer:

LIFELINE HEALTHCARE

Therapeutic class:

Hepatoprotective/Cholagogue (bile acid therapy)

Drug class:

Bile acid (ursodeoxycholic acid)