Vildarise M Tablet

Composition of Vildarise M Tablet

Vildarise M Tablet contains Vildagliptin 50 mg + Metformin Hydrochloride 500 mg (sustained/extended release) tablet. It belongs to the DPP-4 inhibitor + Biguanide class of medicines.

Uses of Vildarise M Tablet

Type 2 diabetes mellitus: to improve blood glucose control in adults when diet and exercise are not sufficient; used when dual therapy with metformin and a DPP-4 inhibitor is appropriate

Key benefits

• Lowers fasting and post-meal blood glucose
• Improves insulin response in a glucose-dependent manner
• Helps reduce hepatic glucose output
• Low risk of hypoglycaemia when used without insulin/sulfonylurea
• Supports long-term HbA1c reduction

How Vildarise M Tablet works

Vildagliptin is a DPP-4 inhibitor that increases incretin hormones (GLP-1, GIP), enhancing glucose-dependent insulin release and reducing glucagon. Metformin decreases hepatic glucose production, reduces intestinal glucose absorption, and improves insulin sensitivity, lowering blood sugar levels.

How to take Vildarise M Tablet

Oral tablet. Take as prescribed, usually once or twice daily with meals to reduce stomach upset (especially due to metformin). Swallow whole; do not crush/chew if SR/ER. Monitor blood glucose regularly and follow diet/exercise advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Vildarise M Tablet

Most side effects of Vildarise M are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhea
• abdominal pain
• loss of appetite
• metallic taste
• headache
• dizziness
• upper respiratory tract infection
• nasopharyngitis

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Vildarise M Tablet

Warnings and precautions

Not for type 1 diabetes or diabetic ketoacidosis. Metformin may rarely cause lactic acidosis—risk higher with kidney impairment, dehydration, severe infection, heart failure, alcohol use, or liver disease; dose adjustment/avoid in renal impairment (check eGFR). Stop temporarily before iodinated contrast procedures and during acute serious illness/surgery as advised by doctor. Vildagliptin: monitor liver enzymes; use caution in hepatic impairment and if symptoms of hepatitis occur. Risk of hypoglycaemia increases when combined with insulin or sulfonylureas. Seek help for severe abdominal pain (pancreatitis) or allergic reactions.

Do not take Vildarise M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases lactic acidosis risk), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide), cationic drugs affecting renal tubular secretion (e.g., cimetidine), insulin/sulfonylureas (increased hypoglycaemia), ACE inhibitors (may increase risk of angioedema with DPP-4 inhibitors), diuretics/corticosteroids/thyroid hormones (may worsen glycaemic control)

How to store Vildarise M Tablet

Store below 25°C in a dry place, protected from moisture and direct light. Keep in original blister and out of reach of children.

Expert advice for Vildarise M Tablet

It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

OWSHADH PHARMACEUTICALS

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide