Vildanat M 500SR Tablet

Composition of Vildanat M 500SR Tablet

Vildanat M 500SR Tablet contains Vildagliptin 50 mg + Metformin Hydrochloride 500 mg (Sustained Release). It belongs to the DPP-4 inhibitor + Biguanide (sustained-release metformin) class of medicines.

Uses of Vildanat M 500SR Tablet

• Type 2 diabetes mellitus (in adults) to improve blood glucose control along with diet and exercise
• especially when metformin alone is inadequate

Key benefits

• Helps lower HbA1c and fasting/post-meal glucose
• Glucose-dependent action with low hypoglycaemia risk when used without sulfonylurea/insulin
• Improves insulin sensitivity and reduces hepatic glucose output
• Convenient sustained-release metformin for prolonged control
• May improve GI tolerability vs immediate-release metformin in some patients

How Vildanat M 500SR Tablet works

Vildagliptin is a DPP-4 inhibitor that increases incretin levels (GLP-1/GIP), enhancing glucose-dependent insulin release and reducing glucagon. Metformin reduces hepatic glucose production and improves insulin sensitivity; the SR form provides prolonged action and may improve gastrointestinal tolerability.

How to take Vildanat M 500SR Tablet

Oral tablet. Usually taken once or twice daily as prescribed, preferably with meals to reduce stomach upset. Swallow whole; do not crush or chew sustained-release tablets. Regularly monitor blood glucose and follow diet/exercise advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Vildanat M 500SR Tablet

Most side effects of Vildanat M 500SR are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhoea
• abdominal pain
• loss of appetite
• headache
• dizziness
• upper respiratory tract infection
• constipation
• flatulence
• skin rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Vildanat M 500SR Tablet

Warnings and precautions

Not for type 1 diabetes or diabetic ketoacidosis. Metformin can rarely cause lactic acidosis—risk increases with kidney impairment, severe infection, dehydration, alcohol use, liver disease, or hypoxia/heart failure; stop and seek care if severe weakness, rapid breathing, abdominal pain, or unusual sleepiness occur. Use with caution/avoid in significant renal impairment; kidney function should be checked before and during therapy. Temporarily withhold metformin before/after iodinated contrast procedures and during major surgery as advised by doctor. Monitor for pancreatitis symptoms (severe persistent abdominal pain) and stop if suspected. Risk of hypoglycaemia increases when used with insulin or sulfonylureas.

Do not take Vildanat M 500SR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Iodinated contrast media, alcohol, insulin and sulfonylureas (increased hypoglycaemia risk), corticosteroids and thiazide/loop diuretics (may raise glucose), beta-blockers (may mask hypoglycaemia symptoms), cimetidine (may increase metformin levels), ACE inhibitors (may enhance glucose-lowering), carbonic anhydrase inhibitors like topiramate/acetazolamide (increased acidosis risk)

How to store Vildanat M 500SR Tablet

Store below 25°C, protected from moisture and light. Keep in original blister pack. Keep out of reach of children.

Expert advice for Vildanat M 500SR Tablet

It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

NATCO

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide (sustained-release metformin)