Vildaprime M 50/500 mg Tablet

Composition of Vildaprime M 50/500 mg Tablet

Vildaprime M 50/500 mg Tablet contains Vildagliptin 50 mg + Metformin hydrochloride 500 mg (tablet). It belongs to the DPP-4 inhibitor + Biguanide class of medicines.

Uses of Vildaprime M 50/500 mg Tablet

Type 2 diabetes mellitus (to improve glycaemic control) when diet and exercise are insufficient; used when metformin alone is not enough or as combination therapy as advised by a doctor.

Key benefits

• Helps lower blood glucose in type 2 diabetes
• Improves post-meal and fasting sugar control
• Lowers liver glucose production and improves insulin sensitivity
• Glucose-dependent action reduces risk of hypoglycaemia compared with some agents (when used alone)

How Vildaprime M 50/500 mg Tablet works

Vildagliptin is a DPP-4 inhibitor that increases incretin hormones (GLP-1, GIP), leading to increased insulin release and reduced glucagon in a glucose-dependent manner. Metformin decreases glucose production by the liver and improves insulin sensitivity, helping the body use glucose better.

How to take Vildaprime M 50/500 mg Tablet

Take orally as prescribed by the physician, usually with meals to reduce stomach upset. Swallow whole with water; do not crush/chew unless advised. Dose and duration depend on blood sugar control, kidney function and tolerability.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause low blood sugar, particularly if you also take other diabetes medicines. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Vildaprime M 50/500 mg Tablet

Most side effects of Vildaprime M 50/500 mg are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhoea
• abdominal pain
• loss of appetite
• metallic taste
• headache
• dizziness
• upper respiratory tract infection
• hypoglycaemia (especially with other antidiabetics)
• fatigue

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Vildaprime M 50/500 mg Tablet

Warnings and precautions

Prescription-only antidiabetic. Metformin may rarely cause lactic acidosis—risk increases with kidney impairment, severe infection, dehydration, alcohol excess, liver disease or heart failure; seek urgent care for fast breathing, severe weakness, abdominal pain. Monitor renal function before and during therapy; avoid/adjust in reduced eGFR as per clinician. Vildagliptin can rarely affect liver enzymes or cause pancreatitis—report persistent severe abdominal pain; periodic LFT monitoring may be advised. Hold metformin temporarily before/after iodinated contrast procedures and during major surgery as advised. Use caution in elderly and those prone to hypoglycaemia when combined with insulin/sulfonylureas.

Do not take Vildaprime M 50/500 mg if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol (increases lactic acidosis risk), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate/acetazolamide), cimetidine and other OCT2/MATE inhibitors (may increase metformin levels), diuretics/ACE inhibitors/NSAIDs (may affect kidney function), corticosteroids and sympathomimetics (may raise glucose), insulin/sulfonylureas (increased hypoglycaemia risk)

How to store Vildaprime M 50/500 mg Tablet

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep in original blister pack and out of reach of children.

Expert advice for Vildaprime M 50/500 mg Tablet

It can be taken with or without food, at the same time each day. Keep up your diet and activity — this medicine supports them. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

PRIMUS PHARMA

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide