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Treatment of eye pain and inflammation after cataract surgery; relief of postoperative ocular inflammation

Nepafenac is a prodrug that penetrates the eye and is converted to amfenac, an NSAID. It inhibits cyclo-oxygenase (COX) enzymes, reducing prostaglandin production and thereby decreasing pain and inflammation.

For ophthalmic use only. Shake well before use. Instill the prescribed number of drops into the affected eye(s) as advised by the doctor, usually 1 drop 3 times daily starting 1 day before cataract surgery, on the day of surgery, and for up to 2 weeks after (or as directed). Remove contact lenses before use and wait at least 15 minutes before reinserting. Do not touch the dropper tip; keep a gap of 5–10 minutes between different eye drops.

Burning/stinging in eye, eye pain, blurred vision, foreign body sensation, sticky eyes, conjunctival redness, itching, increased tearing, headache

Use with caution in patients with bleeding tendency or on anticoagulants (NSAIDs may increase bleeding time). Prolonged use may delay corneal healing and rarely cause corneal adverse events; seek urgent care for worsening pain, vision changes, or increased redness. Avoid use if allergic to nepafenac/other NSAIDs. Not recommended in active ocular infections unless advised by an ophthalmologist. Use caution in dry eye, corneal epithelial defects, or complicated ocular surgeries.

Other topical ophthalmic NSAIDs or corticosteroids (increased risk of delayed healing/corneal effects), anticoagulants/antiplatelets (may increase bleeding risk), concurrent multiple eye drops (separate by 5–10 minutes)

Store below 25°C. Protect from light and moisture. Do not freeze. Keep bottle tightly closed. Discard as per label/typically within 4 weeks of opening.

Nevanac 0.1% Eye Drops, Nepaflam 0.1% Eye Drops, Nepa 0.1% Eye Drops, Nepanac 0.1% Eye Drops, Neparon 0.1% Eye Drops