Overview
Distributor inventory | Tablet
Uses & Benefits
Used to treat high cholesterol (hypercholesterolaemia) and mixed dyslipidaemia; lowers LDL and triglycerides and raises HDL; helps reduce risk of heart attack and stroke in people at risk of cardiovascular disease.
How It Works
Atorvastatin is an HMG‑CoA reductase inhibitor (statin) that reduces cholesterol synthesis in the liver. This increases LDL receptor activity and enhances clearance of LDL cholesterol from the blood, lowering LDL and triglycerides and modestly increasing HDL.
Directions for Use
Oral tablet. Take once daily at the same time each day, with or without food. Continue diet/exercise changes as advised; swallow whole with water. Dose and duration as prescribed; do not stop without medical advice.
Side Effects
Headache, stomach pain, constipation, diarrhoea, nausea, indigestion, muscle pain, weakness, elevated liver enzymes
Warnings & Precautions
Not recommended in pregnancy or breastfeeding. Use with caution in liver disease, heavy alcohol use, hypothyroidism, kidney impairment, and in older adults due to higher muscle side-effect risk. Seek medical help if unexplained muscle pain/tenderness, dark urine, severe fatigue, or jaundice occurs (risk of myopathy/rhabdomyolysis and liver injury). Periodic lipid profile and liver function monitoring may be advised.
Drug Interactions
Strong CYP3A4 inhibitors (clarithromycin, erythromycin, ketoconazole/itraconazole, ritonavir/cobicistat), grapefruit juice (large amounts), cyclosporine, gemfibrozil and other fibrates, niacin (high dose), colchicine, warfarin (monitor INR), diltiazem/verapamil, amiodarone