Moderate to severe bacterial infections such as intra-abdominal infections, respiratory tract infections, urinary tract infections, skin and soft tissue infections, gynecological infections, septicemia (as per susceptibility)
How It Works
Cefoperazone is a third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis. Sulbactam is a beta-lactamase inhibitor that protects cefoperazone from enzymatic breakdown and extends activity against resistant bacteria. The combination improves coverage in mixed and resistant infections.
Frequently Asked Questions
What is this medicine used for?
Moderate to severe bacterial infections such as intra-abdominal infections, respiratory tract infections, urinary tract infections, skin and soft tissue infections, gynecological infections, septicemia (as per susceptibility)
What are the side effects?
Diarrhea, nausea, vomiting, injection site pain, rash, elevated liver enzymes, reduced platelets, positive Coombs test
How does this medicine work?
Cefoperazone is a third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis. Sulbactam is a beta-lactamase inhibitor that protects cefoperazone from enzymatic breakdown and extends activity against resistant bacteria. The combination improves coverage in mixed and resistant infections.
How should I use this medicine?
For IV/IM use only under medical supervision. Dose and frequency depend on severity, site of infection, liver/kidney function, and culture results. Complete the prescribed course.
How should I store this medicine?
Store vial below 25°C, protected from light and moisture. Use reconstituted solution promptly; follow label/hospital protocol for stability.
Do I need a prescription for this product?
Disclaimer
Product information is for awareness only and does not replace medical advice. Do not self-medicate for serious symptoms. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Indian Pharmacopoeia, manufacturer labeling, established medical literature
Availability depends on stock and serviceability.
Directions for Use
For IV/IM use only under medical supervision. Dose and frequency depend on severity, site of infection, liver/kidney function, and culture results. Complete the prescribed course.
Side Effects
Diarrhea, nausea, vomiting, injection site pain, rash, elevated liver enzymes, reduced platelets, positive Coombs test
Warnings & Precautions
Serious allergy risk in cephalosporin/penicillin allergy. Cefoperazone may increase bleeding risk and can cause hypoprothrombinemia; patients with malnutrition, liver disease, or prolonged therapy may need monitoring/vitamin K. Avoid alcohol during and for 72 hours after therapy due to possible disulfiram-like reaction. Use caution in liver impairment and biliary obstruction.
Drug Interactions
Alcohol (disulfiram-like reaction), anticoagulants/antiplatelets (bleeding risk), aminoglycosides (renal risk if co-administered), loop diuretics (kidney risk), oral contraceptives (antibiotics may reduce efficacy in some cases)
Storage Instructions
Store vial below 25°C, protected from light and moisture. Use reconstituted solution promptly; follow label/hospital protocol for stability.
