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Ofloxacin Iv 100Ml [Ronflox] | 198 0

Name: Ofloxacin Iv 100Ml [Ronflox] | 198 0
Brand: Alke
Price: 185.63 INR
Availability: InStock

Overview

Ofloxacin injection (concentration/strength per mL not specified) in 100 mL IV infusion

Uses & benefits

Treatment of susceptible bacterial infections such as complicated urinary tract infections, respiratory tract infections, skin/soft tissue infections, gastrointestinal infections, and other serious infections where IV fluoroquinolone is appropriate

How it works

Ofloxacin is a fluoroquinolone antibiotic. It inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, blocking DNA replication and repair, leading to bacterial cell death.

Directions for use

For intravenous use only. Administer as slow IV infusion over the period recommended in the label/hospital protocol; dose and duration depend on infection type, severity, renal function, and culture sensitivity. Do not mix with incompatible IV fluids/medicines; use under medical supervision.

Side effects

nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, insomnia, injection site reactions, rash, photosensitivity, elevated liver enzymes

Warnings & precautions

Prescription-only antibiotic; use only for proven/suspected bacterial infection. Fluoroquinolones may cause tendonitis/tendon rupture, peripheral neuropathy, CNS effects (seizures, confusion), QT prolongation/arrhythmias, dysglycemia, and severe hypersensitivity. Risk of C. difficile–associated diarrhea. Use with caution in elderly, renal impairment (dose adjustment), history of seizures, myasthenia gravis, and in patients on QT-prolonging drugs. Stop and seek care if tendon pain, neuropathy symptoms, severe diarrhea, or allergic reaction occurs.

Drug interactions

QT-prolonging medicines (e.g., amiodarone, sotalol, macrolides, antipsychotics), corticosteroids (increased tendon rupture risk), antidiabetic drugs/insulin (dysglycemia), warfarin (may increase INR/bleeding risk), NSAIDs (may increase CNS stimulation/seizure risk)

Storage instructions

Store at room temperature as per label (generally below 25°C), protect from light. Do not freeze. Keep container tightly closed and out of reach of children.