Drug | Tablet

Hypertension (high blood pressure)

Cilnidipine is a calcium channel blocker that inhibits L-type calcium channels in vascular smooth muscle, causing vasodilation and lowering blood pressure. It also blocks N-type calcium channels, which may reduce sympathetic nerve activity.

Take once daily as directed by a doctor, preferably at the same time each day. Can be taken with or without food. Do not stop suddenly without medical advice; monitor blood pressure regularly.

Headache, dizziness, flushing, ankle swelling (edema), fatigue, palpitations

Use caution in severe liver impairment and in elderly (risk of dizziness/falls). May cause low blood pressure; caution when driving initially. Inform doctor if you have heart failure, significant aortic stenosis, or are taking multiple antihypertensives. Not for acute hypertensive emergency.

Other antihypertensives (additive hypotension), CYP3A4 inhibitors (e.g., clarithromycin, azole antifungals, ritonavir) may increase levels, CYP3A4 inducers (e.g., rifampicin, phenytoin, carbamazepine) may reduce effect, grapefruit juice (may increase levels)

Store below 25°C in a dry place, away from light and moisture.

Cilacar 5 Tablet, Cilaheart 5 Tablet