Drug | Tablet

Hypertension (high blood pressure), heart failure, prevention of cardiovascular events in stable coronary artery disease

Perindopril is an ACE inhibitor that reduces formation of angiotensin II, leading to relaxation of blood vessels and reduced blood pressure. It also lowers aldosterone, reducing fluid load and easing strain on the heart.

Take as prescribed, usually once daily at the same time each day. Can be taken with or without food; taking before meals is often advised. Swallow whole with water and continue regularly even if you feel well.

Dry cough, dizziness, headache, fatigue, low blood pressure, increased blood potassium, nausea

May cause dizziness/low BP especially after first dose; rise slowly from sitting. Risk of hyperkalemia and kidney function worsening; periodic BP, creatinine and potassium monitoring needed. Avoid in pregnancy; contraindicated with history of angioedema. Seek urgent care for swelling of face/lips/tongue or breathing difficulty.

Potassium supplements/potassium-sparing diuretics (spironolactone, eplerenone), NSAIDs, other antihypertensives/diuretics, lithium, aliskiren, ARBs, trimethoprim

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Coversyl 2 Tablet, Coversyl 8 Tablet