Type 2 diabetes mellitus in adults when diet and exercise alone are insufficient; useful when fasting and post-meal glucose are both elevated requiring dual therapy.
How It Works
Glimepiride closes pancreatic β-cell ATP-sensitive K+ channels (SUR1/Kir6.2), causing depolarisation, Ca2+ influx and insulin release; metformin activates AMPK to reduce hepatic gluconeogenesis and improve peripheral insulin sensitivity.
Directions for Use
Take Glimibrit M 1 Tablet with the first main meal of the day to reduce hypoglycaemia and GI upset; swallow whole with water; dose titration must be done by physician based on glucose readings.
Monitor renal function before and during therapy; stop and seek urgent care for rapid breathing, severe weakness, abdominal pain (lactic acidosis symptoms); counsel on hypoglycaemia recognition and carrying glucose; dose reduction needed in elderly or reduced renal function; avoid dehydration and prolonged fasting; use caution in G6PD deficiency (haemolysis risk with sulfonylureas).
Drug Interactions
Alcohol: increases hypoglycaemia and lactic acidosis risk; iodinated contrast media: precipitates metformin-associated lactic acidosis—hold metformin at/around procedure per protocol; beta-blockers (propranolol/metoprolol): mask hypoglycaemia symptoms; fluoroquinolones (levofloxacin): dysglycaemia; ACE inhibitors: may enhance glucose-lowering effect; sulfonamides/azoles: increase sulfonylurea levels via CYP inhibition.
Storage Instructions
Store at 20–25°C (permitted 15–30°C) in a dry place, protected from moisture and direct light; keep in original blister.
Frequently Asked Questions
What is this medicine used for?
Type 2 diabetes mellitus in adults when diet and exercise alone are insufficient; useful when fasting and post-meal glucose are both elevated requiring dual therapy.
Glimepiride closes pancreatic β-cell ATP-sensitive K+ channels (SUR1/Kir6.2), causing depolarisation, Ca2+ influx and insulin release; metformin activates AMPK to reduce hepatic gluconeogenesis and improve peripheral insulin sensitivity.
How should I use this medicine?
Take Glimibrit M 1 Tablet with the first main meal of the day to reduce hypoglycaemia and GI upset; swallow whole with water; dose titration must be done by physician based on glucose readings.
How should I store this medicine?
Store at 20–25°C (permitted 15–30°C) in a dry place, protected from moisture and direct light; keep in original blister.
Do I need a prescription for this product?
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Can prices or availability change?
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
How do I place an order?
Select a variant, add to cart, enter delivery address, upload prescription if required, and pay securely.
Manufacturer & Brand
Brand:Elbrit LIfe Sciences
Manufacturer:ELBRIT LIFE SCIENCES PVT LTD
HSN Code:30049099
Alternatives
Alternatives are suggested by pharmacists after reviewing your order and prescription.
Disclaimer: Product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
