Macrozide 750

Macrozide 750 contains Pyrazinamide (750mg) and is used for tuberculosis (TB). Prescription required.

Tuberculosis (TB)

Macrozide 750 Tablet is an antitubercular medicine. In the body, it gets converted to pyrazinoic acid. This pyrazinoic acid inhibits fatty acid synthase I (bacterial enzyme), which is essential for bacterial growth. Thus, it works as a bacteriocidal to prohibit their growth and treats tuberculosis.

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macrozide 750 Tablet may be taken with or without food.

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

TB treatment must be taken every day for the whole course, usually six months or more. Stopping early is the main cause of drug-resistant TB, which is far harder to treat. Rifampicin turns urine, sweat and tears orange-red. This is harmless, but it permanently stains soft contact lenses. Report yellowing of the eyes or skin, dark urine, persistent vomiting or severe tiredness at once — the liver needs checking. Report any change in vision, including colour vision, immediately if you are on ethambutol. Rifampicin makes hormonal contraception unreliable. Use an additional method throughout and for a period after the course.

Rifampicin reduces the effect of a very large number of medicines, including contraceptives, blood thinners, steroids, some heart and HIV medicines. Vitamin B6 is usually given alongside isoniazid to prevent nerve damage — take it as prescribed.

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.