Pregabalin + Nortriptyline (strengths vary by brand; commonly Pregabalin 75 mg + Nortriptyline 10 mg)
Tablet
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Tablet · 10`S
Before you take it
Consult doctor (use with caution; generally avoid unless clearly needed)
Avoid
Monograph
Tablet
Neuropathic (nerve) pain such as diabetic neuropathy, post-herpetic neuralgia, sciatica/radiculopathy, neuropathic pain associated with spinal disorders; also used when nerve pain has burning, tingling or shooting character.
Pregabalin reduces abnormal nerve signaling by binding to the alpha-2-delta subunit of voltage-gated calcium channels, decreasing release of pain neurotransmitters. Nortriptyline is a tricyclic antidepressant that increases norepinephrine/serotonin in pain pathways and modulates nerve pain. Together they provide enhanced relief in chronic neuropathic pain.
Tablet; take exactly as prescribed, usually once daily at night (may cause drowsiness). Can be taken with or without food; swallow whole with water. Do not stop suddenly—dose should be tapered by a doctor.
Dizziness, drowsiness/somnolence, dry mouth, constipation, blurred vision, weight gain, peripheral edema (swelling), difficulty concentrating, fatigue
May cause sleepiness, dizziness and blurred vision—avoid driving/operating machinery until effects are known. Use caution in elderly, patients with kidney disease (pregabalin dose adjustment), glaucoma, urinary retention, heart disease/arrhythmias, constipation, and in those with history of substance misuse. Risk of suicidal thoughts/behavior with antiepileptics; seek help for mood changes. Nortriptyline can cause anticholinergic effects and may affect heart rhythm; overdose can be serious. Do not stop abruptly to avoid withdrawal symptoms.
Alcohol and other CNS depressants (opioids, benzodiazepines, antihistamines) increase sedation/respiratory depression; MAO inhibitors (contraindicated/avoid); other antidepressants/serotonergic drugs (risk of serotonin syndrome); anticholinergics (additive dry mouth/constipation/urinary retention); QT-prolonging drugs/antiarrhythmics (arrhythmia risk); tramadol (seizure/serotonin risk); gabapentin (additive dizziness/sedation).
Store below 25°C in a cool, dry place; protect from moisture and light; keep out of reach of children.
Pregain NT, Pregalin NT, Maxgalin NT, Pregaba NT, Pregnid NT
At a glance
Good to know
Neuropathic (nerve) pain such as diabetic neuropathy, post-herpetic neuralgia, sciatica/radiculopathy, neuropathic pain associated with spinal disorders; also used when nerve pain has burning, tingling or shooting character.
Dizziness, drowsiness/somnolence, dry mouth, constipation, blurred vision, weight gain, peripheral edema (swelling), difficulty concentrating, fatigue
Pregabalin reduces abnormal nerve signaling by binding to the alpha-2-delta subunit of voltage-gated calcium channels, decreasing release of pain neurotransmitters. Nortriptyline is a tricyclic antidepressant that increases norepinephrine/serotonin in pain pathways and modulates nerve pain. Together they provide enhanced relief in chronic neuropathic pain.
Tablet; take exactly as prescribed, usually once daily at night (may cause drowsiness). Can be taken with or without food; swallow whole with water. Do not stop suddenly—dose should be tapered by a doctor.
Store below 25°C in a cool, dry place; protect from moisture and light; keep out of reach of children.
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
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Brand
LA LIFE SCIENCES
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Manufacturer: LA LIFE SCIENCES
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance. Sources: Manufacturer labeling, established medical literature (gabapentinoids and tricyclic antidepressants), Indian Pharmacopoeia/general drug monographs
