Wosulin 50/50 Car

Human insulin (premixed) 50% soluble (regular) insulin + 50% isophane (NPH) insulin, strength typically 100 IU/mL (10 mL vial or 3 mL cartridge)

Treatment of diabetes mellitus (Type 1 and Type 2) to control blood glucose levels when insulin therapy is required

This is a premixed human insulin containing short-acting regular insulin for mealtime glucose control and intermediate-acting NPH insulin for basal control. It increases peripheral glucose uptake and reduces hepatic glucose production, thereby lowering blood sugar.

For subcutaneous injection using the prescribed insulin device (cartridge/pen compatible as advised). Dose and timing are individualized; commonly given 1–2 times daily, usually 30 minutes before meals. Roll/tilt gently to resuspend before use; do not shake vigorously. Do not use intravenously.

Hypoglycaemia (low blood sugar), injection site pain/redness/swelling, weight gain, oedema, lipodystrophy, allergic reactions (rash/itching), low potassium (hypokalaemia)

Risk of severe hypoglycaemia—monitor blood glucose and carry fast-acting sugar. Use with caution in kidney or liver impairment, elderly, irregular meal intake, or increased physical activity. Do not use if solution shows clumps/frosting or is not uniformly milky after resuspension. Rotate injection sites to prevent lipodystrophy. Dose may need adjustment during illness, stress, surgery, or change in diet/exercise. Seek urgent help for severe allergy or recurrent hypoglycaemia.

Other antidiabetics (sulfonylureas, metformin) may increase hypoglycaemia risk; beta-blockers may mask hypoglycaemia symptoms; corticosteroids, thiazide diuretics, thyroid hormones, sympathomimetics can raise blood glucose; ACE inhibitors may enhance glucose-lowering; alcohol can increase hypoglycaemia risk; pentamidine may cause hypo- then hyperglycaemia.

Store refrigerated at 2–8°C, do not freeze. Protect from light. Once in use, store as per label (often below 25–30°C) and use within recommended in-use period; keep away from heat and moisture.

Huminsulin 50/50 Cartridge, Insuman Comb 50 Cartridge, Mixtard 50/50 Penfill, Actraphane 50/50 Penfill