Hypoglycaemia (low blood sugar),injection site reactions (pain, redness, swelling),weight gain,lipodystrophy (skin thickening/pitting),edema,allergic reactions (rash/itching)

Risk of severe hypoglycaemia—monitor blood glucose regularly and carry fast-acting sugar. Use caution when changing insulin dose/brand, meal patterns, or activity. Dose adjustment may be needed in kidney/liver impairment, illness, stress, or with other antidiabetics. Do not use during episodes of hypoglycaemia. Seek urgent care for severe allergy or recurrent unexplained hypoglycaemia.

Other antidiabetics (sulfonylureas, GLP-1 agents) increase hypoglycaemia risk; beta-blockers may mask hypoglycaemia symptoms; corticosteroids, thiazide/loop diuretics, thyroid hormones, sympathomimetics can raise glucose and reduce insulin effect; ACE inhibitors can increase insulin sensitivity; alcohol increases hypoglycaemia risk

Unopened: store refrigerated at 2–8°C; do not freeze; protect from light. In-use cartridge: keep as per label, typically below 25–30°C away from heat/light; do not refrigerate if in use; discard after recommended in-use period. Keep out of reach of children.

Huminsulin R 100IU/ml Cartridge,Insugen-R 100IU/ml Cartridge,Actrapid 100IU/ml Penfill,Human Mixtard/other alternatives not equivalent (consult doctor)