Esiflo 250 Transcaps

Composition of Esiflo 250 Transcaps

Esiflo 250 Transcaps contains Salmeterol (50mcg) + Fluticasone Propionate (250mcg). It belongs to the Inhaled corticosteroid (ICS) + long-acting beta-2 agonist (LABA) class of medicines.

Uses of Esiflo 250 Transcaps

• Maintenance treatment of asthma
• Maintenance treatment of chronic obstructive pulmonary disease (COPD) including chronic bronchitis and emphysema (where inhaled corticosteroid/LABA combination is indicated)

Key benefits

• Controls and prevents asthma symptoms
• Reduces airway inflammation
• Improves breathing and lung function
• Decreases frequency of wheezing/shortness of breath
• Helps prevent COPD exacerbations (when indicated)

How Esiflo 250 Transcaps works

Fluticasone is an inhaled corticosteroid that reduces airway inflammation, swelling and mucus production. Formoterol is a long-acting beta-2 agonist (LABA) that relaxes airway smooth muscles to keep airways open for easier breathing. Together they prevent symptoms like wheeze and breathlessness when used regularly.

How to take Esiflo 250 Transcaps

For inhalation use only via a compatible dry powder inhaler/rotahaler-type device; do not swallow the capsule. Use exactly as prescribed, usually at the same time each day. Rinse mouth/gargle with water after each use and spit out to reduce risk of oral thrush.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause a racing heart, marked tremor, headache and a fall in blood potassium. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Esiflo 250 Transcaps

Most side effects of Esiflo are mild and settle as the body adjusts. Reported side effects include:

• Throat irritation
• hoarseness
• cough
• headache
• oral thrush (candidiasis)
• tremor
• palpitations
• nausea

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Esiflo 250 Transcaps

Warnings and precautions

Not for relief of sudden asthma attack/acute bronchospasm—keep a rescue inhaler (e.g., salbutamol). Do not exceed prescribed dose; LABA overuse can be harmful. Rinse mouth after use to prevent fungal infection. Use with caution in heart disease, arrhythmias, hypertension, hyperthyroidism, diabetes, seizures, glaucoma, tuberculosis or untreated infections. Long-term/high-dose inhaled steroids may cause adrenal suppression, reduced bone mineral density, cataract/glaucoma, and growth suppression in children. Seek medical help if breathing worsens, increased need for rescue inhaler, or signs of pneumonia in COPD.

Do not take Esiflo if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to the propellant used in the inhaler.

Interactions with other medicines

Beta-blockers (may reduce effect/trigger bronchospasm),other LABAs/adrenergic drugs (additive cardiovascular effects),MAO inhibitors or tricyclic antidepressants (enhanced sympathomimetic effects),strong CYP3A4 inhibitors like ritonavir/cobicistat/ketoconazole/itraconazole (increase fluticasone systemic effects),diuretics (hypokalemia risk),xanthines like theophylline (hypokalemia risk)

How to store Esiflo 250 Transcaps

Store below 25°C in a dry place, protected from moisture and direct light. Keep capsules in blister until use. Keep out of reach of children.

Expert advice for Esiflo 250 Transcaps

Keep a spare reliever and check the counter so you are not caught with an empty one. Follow your written asthma action plan if you have one. Do not stop a preventer because you feel better — that is the medicine working.

Manufacturer and class

Manufacturer:

Lupin Ltd

Therapeutic class:

Anti-asthmatic / COPD (inhaled corticosteroid + bronchodilator)

Drug class:

Inhaled corticosteroid (ICS) + long-acting beta-2 agonist (LABA)