Glimedose M1 Tablet

Composition of Glimedose M1 Tablet

Glimedose M1 Tablet contains Glimepiride (2mg) + Metformin (500mg). It belongs to the Sulfonylurea + Biguanide (combination) class of medicines.

Uses of Glimedose M1 Tablet

Treatment of type 2 diabetes mellitus in adults when diet and exercise alone are insufficient; helps control blood glucose as combination therapy.

Key benefits

• Lowers fasting and post-meal blood glucose
• Improves insulin secretion and sensitivity
• Helps achieve better HbA1c control than monotherapy
• May reduce diabetes-related complications with sustained control

How Glimedose M1 Tablet works

Glimepiride is a sulfonylurea that increases insulin release from the pancreas and improves insulin action. Metformin decreases glucose production in the liver and improves insulin sensitivity, reducing intestinal glucose absorption. Together they lower fasting and post-meal blood sugar.

How to take Glimedose M1 Tablet

Take orally exactly as prescribed, usually with meals to reduce stomach upset and lower risk of hypoglycaemia. Swallow tablet whole with water; do not skip meals. Dose is individualized based on blood glucose; regular monitoring is required.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe and prolonged low blood sugar, which may lead to fits or unconsciousness. It can cause a dangerous build-up of acid in the blood, with vomiting, severe weakness and laboured breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Glimedose M1 Tablet

Most side effects of Glimedose M1 are mild and settle as the body adjusts. Reported side effects include:

• Hypoglycaemia
• nausea
• vomiting
• diarrhoea
• abdominal pain
• loss of appetite
• headache
• dizziness
• weight gain

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Glimedose M1 Tablet

Warnings and precautions

Risk of hypoglycaemia (especially if meals are missed, after exercise, or with alcohol); monitor blood glucose. Metformin may rarely cause lactic acidosis—risk increases with severe kidney impairment, dehydration, severe infection, heart/respiratory failure or excessive alcohol; assess renal function before and during therapy. Use caution in liver disease; stop temporarily before/after iodinated contrast procedures and major surgery as advised by doctor. Avoid if type 1 diabetes or diabetic ketoacidosis; seek medical help for symptoms of low sugar or lactic acidosis (rapid breathing, severe weakness, abdominal discomfort).

Do not take Glimedose M1 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for type 1 diabetes or for diabetic ketoacidosis. Not for people with severe kidney or liver disease. Not for people with severe kidney disease, severe liver disease, or an acute illness causing dehydration. Not for people who have had diabetic ketoacidosis.

Interactions with other medicines

Alcohol, insulin/other antidiabetics (risk of hypoglycaemia), beta-blockers (may mask hypoglycaemia symptoms), corticosteroids and thiazide/loop diuretics (may raise glucose), ACE inhibitors (may enhance glucose-lowering), fluoroquinolones (glucose disturbances), rifampicin (may reduce effect), azole antifungals and macrolides (may increase sulfonylurea effect), iodinated contrast media (metformin—lactic acidosis risk), cimetidine (may increase metformin levels)

How to store Glimedose M1 Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Expert advice for Glimedose M1 Tablet

Take it shortly before a meal, and eat that meal. Check your sugar as often as your doctor has asked, especially when your routine changes. Take it with or just after food to reduce stomach upset. Keep taking it even when your sugar readings look normal — that is the medicine working. Continue your diet and physical activity; this medicine works alongside them, not instead of them.

Manufacturer and class

Manufacturer:

MSV LIFESCIENCES

Therapeutic class:

Antidiabetic

Drug class:

Sulfonylurea + Biguanide (combination)