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Abbott India Limited - Sachet - 6 G
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Human insulin (rDNA origin) 40 IU/mL (Regular/soluble insulin) injection
Delivered across India in about 3–5 days, Chennai next day. ₹49 delivery, free above ₹999.
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Human Actrapid 40 10 ml is used for treatment of diabetes mellitus (Type 1 and Type 2) to control high blood glucose; management of diabetic ketoacidosis (under medical supervision); perioperative/acute illness hyperglycaemia as directed by a doctor.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Human Actrapid 40 10 ml contains Human insulin (rDNA origin) 40 IU/mL (Regular/soluble insulin) injection. It belongs to the Short-acting insulin (Regular human insulin) class of medicines.
Treatment of diabetes mellitus (Type 1 and Type 2) to control high blood glucose; management of diabetic ketoacidosis (under medical supervision); perioperative/acute illness hyperglycaemia as directed by a doctor
Regular human insulin replaces/supplements insulin in the body. It helps glucose enter muscle and fat cells and reduces glucose production by the liver, thereby lowering blood sugar levels. It is a short-acting insulin with relatively quick onset and shorter duration compared with intermediate/long-acting insulins.
Subcutaneous injection as prescribed, usually 30 minutes before meals. Dose is individualized based on blood glucose, diet and activity; rotate injection sites (abdomen, thigh, upper arm). May be used IV only in hospital settings by trained professionals; use only insulin syringes calibrated for U-40 insulin.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Contact your doctor or diabetes nurse for advice — do not take a double dose to make up for a missed injection.
An overdose of this medicine can cause severe low blood sugar, leading to fits or unconsciousness — this is a medical emergency. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Human Actrapid are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Generally safe (insulin is preferred in pregnancy; dose adjustments may be needed—consult doctor) |
|---|---|
| Breastfeeding | Generally considered safe while breastfeeding. |
| Alcohol | Use with caution (alcohol can cause delayed hypoglycaemia) |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Hypoglycaemia is the most important risk—carry glucose/sugar and monitor blood glucose regularly. Use correct strength (U-40) and matching syringe to avoid dosing errors; do not share needles/syringes. Caution in renal or hepatic impairment, elderly, irregular meals, increased exercise, and in patients with autonomic neuropathy (reduced hypoglycaemia warning signs). Seek urgent care for severe allergy, recurrent severe hypoglycaemia, or hyperglycaemia/ketosis symptoms; do not stop insulin abruptly.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not to be used during an episode of low blood sugar.
Other antidiabetics (additive hypoglycaemia), beta-blockers (may mask hypoglycaemia), ACE inhibitors/ARBs (may increase hypoglycaemia risk), corticosteroids/thyroid hormones/oral contraceptives/thiazide diuretics (may increase blood glucose), MAO inhibitors/salicylates (may enhance insulin effect), alcohol (can cause hypoglycaemia), sympathomimetics (may raise glucose)
Unopened vials: store refrigerated at 2–8°C; do not freeze. Protect from light. After opening/in-use: keep as per label (often refrigerated or at room temperature below 25–30°C) and discard after the in-use period; keep vial tightly closed and avoid heat.
Keep an unopened supply in the fridge and the pen in use at room temperature, away from direct sunlight. Always carry a fast-acting sugar source. Check your sugar as your doctor has instructed, and keep a record to take to appointments.

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.