Prescription requiredNeuropathic pain agent / Neurovitamin

Pregain M — Uses, Dosage & Benefits

Pregain M is used for Neuropathic pain (e.g., diabetic peripheral neuropathy, post-herpetic neuralgia), nerve pain associated with vitamin B12 deficiency, tingling/numbness due to peripheral neuropathy.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

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Active Ingredient / Composition

Pregabalin 75 mg + Methylcobalamin (Mecobalamin) 750 mcg (capsule)

What is Pregain M used for?

Neuropathic pain (e.g.
diabetic peripheral neuropathy
post-herpetic neuralgia)
nerve pain associated with vitamin B12 deficiency
tingling/numbness due to peripheral neuropathy

How Pregain M Works

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the CNS, reducing release of excitatory neurotransmitters and thereby decreasing neuropathic pain. Methylcobalamin is an active form of vitamin B12 that supports myelin formation and nerve repair, helping improve nerve function.

Dosage & Directions

Take orally as prescribed by the doctor, usually once or twice daily. Can be taken with or without food; take at the same time each day. Swallow capsule whole; do not crush or chew. Do not stop suddenly—taper as advised.

Always follow your doctor's prescription. Do not self-medicate.

Key Benefits

Relieves neuropathic (nerve) pain
Reduces tingling and burning sensations
Improves numbness due to peripheral neuropathy
Supports nerve repair and myelin health
Helps improve quality of sleep disturbed by nerve pain

Pregnancy

Use with caution / Consult doctor

Alcohol Interaction

Avoid

Pregain M — Quick Facts

Composition: Pregabalin 75 mg + Methylcobalamin (Mecobalamin) 750 mcg (capsule)
Therapeutic class: Neuropathic pain agent / Neurovitamin
Drug class: Gabapentinoid (pregabalin) + Vitamin B12 analog (methylcobalamin)
Prescription: Required (Rx)
Price: ₹158
Habit forming: No
Storage: Store below 25°C in a cool, dry place away from moisture and direct light. Keep in original pack and out of reach of children.

Pregain M — Usage FAQs

How should I take this medicine?

Follow the dosage prescribed by your doctor. Do not alter the dose without medical advice.

Can I take this medicine without a prescription?

Prescription-required medicines need a valid Rx. OTC medicines can be purchased directly.

What if I miss a dose?

Take the missed dose as soon as you remember, unless it is close to your next scheduled dose. Do not double the dose.

How long does it take to show effect?

The time to show effect varies by medicine and condition. Consult your doctor for specific timelines.

Pregain M — Uses, Dosage & Benefits

Active Ingredient / Composition

What is Pregain M used for?

How Pregain M Works

Dosage & Directions

Key Benefits

Pregnancy

Alcohol Interaction

Pregain M — Quick Facts

Pregain M — Usage FAQs

More from PingMeDoc™

Safety disclaimer

Pregain M — Uses, Dosage & Benefits

Active Ingredient / Composition

What is Pregain M used for?

How Pregain M Works

Dosage & Directions

Key Benefits

Pregnancy

Alcohol Interaction

Pregain M — Quick Facts

Pregain M — Usage FAQs

More from PingMeDoc™

Safety disclaimer