Pregain M

Composition of Pregain M

Pregain M contains Pregabalin 75 mg + Methylcobalamin (Mecobalamin) 750 mcg (capsule). It belongs to the Gabapentinoid (pregabalin) + Vitamin B12 analog (methylcobalamin) class of medicines.

Uses of Pregain M

• Neuropathic pain (e.g.
• diabetic peripheral neuropathy
• post-herpetic neuralgia)
• nerve pain associated with vitamin B12 deficiency
• tingling/numbness due to peripheral neuropathy

Key benefits

• Relieves neuropathic (nerve) pain
• Reduces tingling and burning sensations
• Improves numbness due to peripheral neuropathy
• Supports nerve repair and myelin health
• Helps improve quality of sleep disturbed by nerve pain

How Pregain M works

Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the CNS, reducing release of excitatory neurotransmitters and thereby decreasing neuropathic pain. Methylcobalamin is an active form of vitamin B12 that supports myelin formation and nerve repair, helping improve nerve function.

How to take Pregain M

Take orally as prescribed by the doctor, usually once or twice daily. Can be taken with or without food; take at the same time each day. Swallow capsule whole; do not crush or chew. Do not stop suddenly—taper as advised.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause deep drowsiness, confusion, unsteadiness and slowed breathing, especially with an opioid or alcohol. It is unlikely to cause serious harm, because the body passes surplus B vitamins out in the urine. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Pregain M

Most side effects of Pregain M are mild and settle as the body adjusts. Reported side effects include:

• Dizziness
• drowsiness/somnolence
• blurred vision
• dry mouth
• weight gain
• peripheral edema (swelling)
• constipation
• difficulty concentrating

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Pregain M

Warnings and precautions

May cause dizziness and sleepiness—avoid driving or operating machinery until you know its effects. Use with caution in kidney disease (dose adjustment may be needed). Risk of swelling/edema and weight gain; caution in heart failure. Do not stop abruptly (may cause withdrawal symptoms). Rarely may cause mood changes/suicidal thoughts—seek medical help if depression, unusual behavior, or self-harm thoughts occur. Hypersensitivity reactions (rash, facial swelling) require urgent care.

Do not take Pregain M if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Alcohol and other CNS depressants (increased sedation), opioids (e.g., morphine, tramadol—higher risk of sedation/respiratory depression), benzodiazepines, antihistamines (sedation), other antiepileptics (additive dizziness), antidiabetic thiazolidinediones like pioglitazone/rosiglitazone (increased edema/weight gain)

How to store Pregain M

Store below 25°C in a cool, dry place away from moisture and direct light. Keep in original pack and out of reach of children.

Expert advice for Pregain M

Take the larger part of the dose at night if drowsiness is a problem. Rise slowly from sitting or lying, especially in the first weeks. Keep your review appointment so the dose can be adjusted to the lowest that controls your pain. A supplement corrects a deficiency; it is not a general energy tonic. If you are on it for nerve symptoms, keep your review appointment so the underlying cause is looked for.

Manufacturer and class

Manufacturer:

LA LIFE SCIENCES

Therapeutic class:

Neuropathic pain agent / Neurovitamin

Drug class:

Gabapentinoid (pregabalin) + Vitamin B12 analog (methylcobalamin)