Tolvat 30 mg 15S+15Free

Composition of Tolvat 30 mg 15S+15Free

Tolvat 30 mg 15S+15Free contains Tolvaptan 30 mg (tablet). It belongs to the Selective vasopressin V2 receptor antagonist class of medicines.

Uses of Tolvat 30 mg 15S+15Free

• Treatment of hyponatremia (low blood sodium) associated with conditions like heart failure
• liver cirrhosis and SIADH (syndrome of inappropriate antidiuretic hormone secretion); used under medical supervision to raise serum sodium.

Key benefits

• Raises low serum sodium in euvolemic/hypervolemic hyponatremia
• Promotes excretion of excess free water
• Helps reduce fluid overload without major electrolyte loss
• Improves symptoms related to hyponatremia (as appropriate)

How Tolvat 30 mg 15S+15Free works

Tolvaptan is a selective vasopressin V2-receptor antagonist. It blocks the action of antidiuretic hormone in the kidneys, increasing excretion of free water (aquaresis) without significant loss of electrolytes, thereby increasing serum sodium.

How to take Tolvat 30 mg 15S+15Free

Take as prescribed by a doctor, usually once daily. Can be taken with or without food; swallow whole with water. Initiation and dose changes are typically done with close monitoring of sodium and hydration status; maintain adequate access to water and drink when thirsty.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe dehydration, a sharp fall in blood pressure and dangerous salt imbalances. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Tolvat 30 mg 15S+15Free

Most side effects of Tolvat are mild and settle as the body adjusts. Reported side effects include:

• Thirst
• dry mouth
• increased urination (polyuria)
• frequent urination
• dehydration
• dizziness
• weakness
• constipation
• increased blood sodium (hypernatremia)

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Tolvat 30 mg 15S+15Free

Warnings and precautions

Use only under specialist supervision with regular monitoring of serum sodium to avoid overly rapid correction (risk of serious neurological injury). Risk of dehydration and low blood pressure—ensure adequate fluid intake. Tolvaptan can cause serious liver injury in some uses; monitor liver function if advised and stop if symptoms like fatigue, loss of appetite, right upper abdominal pain, dark urine or jaundice occur. Avoid in anuria, inability to sense/respond to thirst, hypovolemic hyponatremia, urgent need to raise sodium, or severe liver disease unless specifically directed. Use caution in kidney disease, elderly, and with diuretics.

Do not take Tolvat if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people who are unable to pass urine, or who are severely dehydrated.

Interactions with other medicines

Strong CYP3A inhibitors (ketoconazole, itraconazole, clarithromycin, ritonavir), CYP3A inducers (rifampicin, phenytoin, carbamazepine, St John’s wort), other diuretics, digoxin (may increase levels), grapefruit juice

How to store Tolvat 30 mg 15S+15Free

Store at room temperature (below 25°C), in a dry place, protected from moisture and light. Keep out of reach of children.

Expert advice for Tolvat 30 mg 15S+15Free

Weigh yourself at the same time each day if you have heart failure, and report a rapid gain. Do not add extra salt, and ask before using a potassium-based salt substitute.

Manufacturer and class

Manufacturer:

MSN LABORATORIES

Therapeutic class:

Vasopressin antagonist / Aquaretic (for hyponatremia)

Drug class:

Selective vasopressin V2 receptor antagonist