Prescription requiredAntidiabetic

Zoryl Mp-2 — Uses, Dosage & Benefits

Zoryl Mp-2 is used for Type 2 diabetes mellitus in adults (when diet and exercise alone or dual therapy is not adequate) to improve blood glucose control.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated August 2026

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Active Ingredient / Composition

Glimepiride 2 mg + Metformin Hydrochloride 500 mg (Sustained Release) + Pioglitazone 15 mg (tablet)

What is Zoryl Mp-2 used for?

Type 2 diabetes mellitus in adults (when diet and exercise alone or dual therapy is not adequate) to improve blood glucose control

How Zoryl Mp-2 Works

Glimepiride (sulfonylurea) increases insulin release from pancreatic beta cells. Metformin SR reduces glucose production in the liver and improves insulin sensitivity. Pioglitazone (PPAR-gamma agonist) increases insulin sensitivity in muscle and fat, improving glucose uptake.

Dosage & Directions

Take by mouth as prescribed, usually once daily with the first main meal. Swallow whole; do not crush or chew (SR tablet). Monitor blood glucose regularly and follow diet/exercise advice.

Always follow your doctor's prescription. Do not self-medicate.

Key Benefits

Lowers fasting and post-meal blood sugar
Improves insulin sensitivity
Helps reduce HbA1c
Triple-action control for type 2 diabetes

Pregnancy

Not recommended; consult doctor (insulin preferred in pregnancy)

Alcohol Interaction

Avoid (risk of hypoglycaemia and metformin-associated lactic acidosis)

Zoryl Mp-2 — Quick Facts

Composition: Glimepiride 2 mg + Metformin Hydrochloride 500 mg (Sustained Release) + Pioglitazone 15 mg (tablet)
Therapeutic class: Antidiabetic
Drug class: Sulfonylurea + Biguanide + Thiazolidinedione (PPAR-gamma agonist)
Prescription: Required (Rx)
Price: ₹319
Habit forming: No
Storage: Store below 25°C, protect from moisture and light, keep in original strip/container. Keep out of reach of children.

Zoryl Mp-2 — Usage FAQs

How should I take this medicine?

Follow the dosage prescribed by your doctor. Do not alter the dose without medical advice.

Can I take this medicine without a prescription?

Prescription-required medicines need a valid Rx. OTC medicines can be purchased directly.

What if I miss a dose?

Take the missed dose as soon as you remember, unless it is close to your next scheduled dose. Do not double the dose.

How long does it take to show effect?

The time to show effect varies by medicine and condition. Consult your doctor for specific timelines.