Angizem Dp 120

Diltiazem (120mg)

Hypertension (high blood pressure), chronic stable angina (chest pain due to coronary artery disease), vasospastic/Prinzmetal angina

Diltiazem is a calcium channel blocker that relaxes blood vessels and reduces the workload of the heart. It also slows conduction through the AV node, which can help control heart rate in some patients.

Take exactly as prescribed, usually once daily at the same time. Swallow the prolonged-release tablet/capsule whole; do not crush, chew or split. May be taken with or without food; avoid grapefruit/grapefruit juice.

Headache, dizziness, flushing, ankle swelling (edema), constipation, nausea, tiredness, low blood pressure, slow heart rate

Do not use in severe hypotension, sick sinus syndrome or 2nd/3rd degree AV block without a pacemaker. Use with caution in heart failure/left ventricular dysfunction, liver or kidney disease, and in the elderly (risk of bradycardia/hypotension). Do not stop suddenly without medical advice. Seek urgent care for fainting, very slow pulse, worsening breathlessness or swelling, chest pain, or allergic reaction.

Beta-blockers (e.g., metoprolol, propranolol) and digoxin (risk of bradycardia/AV block), other antihypertensives (additive BP lowering), CYP3A4 inhibitors (e.g., erythromycin/clarithromycin, azole antifungals, ritonavir) increase diltiazem levels, CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin) reduce effect, statins (simvastatin/atorvastatin) increased levels/myopathy risk, cyclosporine/tacrolimus increased levels

Store below 25°C in a dry place, protected from light and moisture. Keep in original pack and out of reach of children.

Cardizem CD 120, Dilzem SR 120, Diltiazem SR 120 (generic), Tildiem SR 120, Dilti SR 120