CONFLU 200MG CAP

Distributor inventory | Capsule

Treatment of fungal infections such as candidiasis (oral/throat, vaginal, systemic), cryptococcal infections (including meningitis), and prevention of fungal infections in immunocompromised patients (as prescribed).

Fluconazole is a triazole antifungal that inhibits fungal CYP450 enzyme 14‑alpha‑demethylase, reducing ergosterol synthesis. This disrupts the fungal cell membrane, stopping growth and leading to fungal cell death.

Capsule for oral use. Take exactly as prescribed, usually once daily; may be taken with or without food. Swallow whole with water and complete the full course; dose and duration depend on infection type and kidney function.

Nausea, abdominal pain, diarrhoea, headache, dizziness, rash, vomiting, taste changes, increased liver enzymes

Prescription-only antifungal. Use with caution in liver disease (risk of hepatitis), kidney impairment (dose adjustment may be needed), and in patients with heart rhythm problems/long QT (risk of QT prolongation). Stop and seek care if severe rash/blistering, jaundice, dark urine, persistent vomiting, or allergic reaction occurs. Not for self-treatment of undiagnosed infections; ensure correct diagnosis.

Warfarin/other anticoagulants (↑bleeding), phenytoin, carbamazepine, cyclosporine, tacrolimus, sulfonylureas (hypoglycaemia), rifampicin (↓fluconazole levels), zidovudine, theophylline, statins (e.g., simvastatin/atorvastatin—↑myopathy risk), benzodiazepines (e.g., midazolam), QT-prolonging drugs (e.g., amiodarone, quinidine, erythromycin). Contraindicated/avoid with drugs highly dependent on CYP3A4 that prolong QT (e.g., cisapride, terfenadine at high doses, pimozide) where applicable.

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

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