Encorate 300 Tablet

Drug | Tablet

Epilepsy/seizure disorders, bipolar disorder (mania) as prescribed, prevention of migraine (selected patients as prescribed)

Valproate increases inhibitory neurotransmission in the brain (enhances GABA activity) and reduces neuronal excitability. This helps control seizures and stabilizes mood in bipolar disorder.

Take exactly as prescribed, preferably with food to reduce stomach upset. Swallow tablets whole; do not crush or chew (especially if enteric-coated). Regular monitoring may be needed (liver function, blood counts, valproate level in some cases).

Nausea, vomiting, abdominal pain, indigestion, diarrhea, tremor, drowsiness, dizziness, weight gain, hair loss, increased appetite

High risk of birth defects and developmental disorders; avoid in pregnancy unless no alternative and under specialist care. Risk of serious liver injury (especially in young children), pancreatitis, hyperammonemia/encephalopathy, thrombocytopenia and bleeding; monitor symptoms and labs. Use caution in liver disease, mitochondrial disorders, and with other CNS depressants.

Lamotrigine (increased risk of severe rash), carbamazepine/phenytoin/phenobarbital (level changes), topiramate (hyperammonemia), warfarin/antiplatelets (bleeding risk), aspirin (increases valproate levels), benzodiazepines and alcohol (added sedation)

Store below 25°C in a dry place, protected from light. Keep out of reach of children.

Valparin 300 Tablet, Valprol 300 Tablet, Encorate 300 Tablet (same brand), Epival 300 Tablet, Divalproex/Valproate 300 mg equivalents