Jubiglim M2 Forte

Glimepiride 2 mg + Metformin Hydrochloride 1000 mg (extended-release/sustained-release)

Type 2 diabetes mellitus when diet and exercise alone are not sufficient; helps control high blood sugar and improve glycaemic control.

Glimepiride (a sulfonylurea) stimulates the pancreas to release more insulin. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity, lowering blood glucose levels.

Oral tablet. Usually taken once daily with the first main meal (or as directed by doctor). Swallow whole; do not crush/chew (especially if ER/SR). Take at the same time each day and follow prescribed diet/exercise plan.

Nausea, diarrhoea, abdominal discomfort, decreased appetite, metallic taste, headache, dizziness, hypoglycaemia (low blood sugar), weight gain

Prescription-only antidiabetic. Risk of hypoglycaemia (higher with missed meals, alcohol, strenuous exercise, elderly, or with other antidiabetics). Metformin can rarely cause lactic acidosis—seek urgent care for rapid breathing, severe weakness, abdominal pain, vomiting, or unusual sleepiness. Avoid/use with caution in severe kidney impairment; monitor renal function before and during therapy. Use caution in liver disease, heart failure, dehydration, severe infection, or low oxygen states. Temporarily stop metformin before/after iodinated contrast procedures or major surgery as advised by doctor. Monitor blood glucose and HbA1c regularly.

Alcohol (increases risk of hypoglycaemia and lactic acidosis), insulin/other antidiabetics (increased hypoglycaemia), beta-blockers (may mask hypoglycaemia symptoms), corticosteroids and thiazide/loop diuretics (may raise blood glucose), ACE inhibitors (may increase hypoglycaemia risk), quinolones (may alter glucose), cimetidine (may increase metformin levels), iodinated contrast media (risk of kidney injury/lactic acidosis), NSAIDs and other highly protein-bound drugs (may increase sulfonylurea effect)

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

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