Linabite-Dm 5/10/1000MG Tab

Tablet

Type 2 diabetes mellitus: to improve glycaemic control in adults when diet and exercise are not enough; used as combination therapy when multiple agents are required.

Linagliptin is a DPP-4 inhibitor that increases incretin hormones, boosting glucose-dependent insulin release and reducing glucagon. Dapagliflozin is an SGLT2 inhibitor that increases urinary glucose excretion. Metformin reduces hepatic glucose production and improves insulin sensitivity.

Oral tablet; take exactly as prescribed by physician. Usually taken once daily with food (especially if metformin/ER) to reduce stomach upset; swallow whole if extended-release—do not crush or chew. Maintain adequate hydration and follow diet/exercise advice.

Nausea, vomiting, diarrhoea, abdominal discomfort, decreased appetite, headache, dizziness, increased urination, genital fungal infection, urinary tract infection

Prescription-only antidiabetic. Metformin: risk of lactic acidosis—avoid in severe kidney impairment; caution in liver disease, alcohol use, dehydration and severe infection; temporarily stop before iodinated contrast/surgery as advised. Dapagliflozin: may cause dehydration, hypotension, genital mycotic infections, UTIs and rare ketoacidosis (can occur with near-normal glucose); monitor renal function and stop if symptoms of ketoacidosis occur. Linagliptin: rare pancreatitis/serious hypersensitivity; seek care for severe abdominal pain or rash. Not for type 1 diabetes or diabetic ketoacidosis. Monitor blood glucose, HbA1c and kidney function regularly.

Alcohol (increases lactic acidosis risk with metformin), iodinated contrast media, diuretics/antihypertensives (dehydration/hypotension), insulin or sulfonylureas (hypoglycaemia risk when combined), systemic corticosteroids (raise glucose), rifampicin/strong enzyme inducers (may reduce linagliptin effect), other SGLT2 inhibitors/DPP-4 inhibitors (duplicate therapy).

Store below 25°C, in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Glyxambi Duo 5/10/1000 Tablet, Trijardy XR 5/10/1000 Tablet, Linaglip D M 5/10/1000 Tablet, Linaday DM 5/10/1000 Tablet, Linagliptin Dapagliflozin Metformin 5/10/1000 Tablets (generic)