
Nexpro Fast 40
10 S

Torrent Pharmaceuticals Ltd
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Pantoprazole 40 mg (as enteric-coated), Domperidone 30 mg (as sustained release) capsule
Zipant -D SR contains Pantoprazole 40 mg (as enteric-coated), Domperidone 30 mg (as sustained release) capsule and is used for gastroesophageal reflux disease (GERD), heartburn and acid reflux. Prescription required.
Monograph
Zipant -D SR is a prescription medicine containing Pantoprazole 40 mg (as enteric-coated), Domperidone 30 mg (as sustained release) capsule. It is used for gastroesophageal reflux disease (GERD), heartburn, acid reflux, gastritis, acid-peptic disorders, nausea and vomiting associated with reflux or delayed gastric emptying. It belongs to the group of medicines called Proton pump inhibitor + Prokinetic (peripheral D2 antagonist).
Take as directed by doctor. The dose and how long you take it depend on what you are being treated for and how you respond. Do not take more, or for longer, than your doctor has advised.
The side effects seen most often with Zipant -D SR are headache, diarrhoea, abdominal pain and nausea. Most are mild and settle as the body gets used to the medicine. Tell your doctor if one persists or worries you.
Before you start, tell your doctor about any liver, kidney or heart problem, whether you are pregnant, planning a pregnancy or breastfeeding, and every other medicine you take, including supplements and ayurvedic preparations. Some of them can change how Zipant -D SR works.
Most side effects of Zipant -D SR are mild and settle as the body gets used to the medicine. The ones reported most often are:
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Take as directed by doctor. Usually 1 capsule once daily, preferably 30 minutes before breakfast; swallow whole and do not crush/chew (SR/enteric-coated).
Pantoprazole is a proton pump inhibitor that reduces stomach acid by blocking the H+/K+ ATPase pump in gastric parietal cells. Domperidone is a peripheral dopamine (D2) antagonist that increases gastric motility and helps relieve nausea by enhancing gastric emptying.
Use with caution in liver disease. Domperidone may increase risk of QT prolongation/serious arrhythmias—avoid in patients with known QT prolongation, significant electrolyte disturbances, or underlying cardiac disease; do not exceed prescribed dose. Long-term PPI use may be associated with low magnesium/vitamin B12, bone fracture risk, and C. difficile-associated diarrhoea; report persistent diarrhoea. Seek medical advice if alarm symptoms occur (weight loss, vomiting blood, black stools, difficulty swallowing).
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine may cause confusion, blurred vision, sweating and a fast heartbeat. It can cause drowsiness, disorientation and abnormal muscle movements. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
QT-prolonging drugs (e.g., amiodarone, sotalol, certain antipsychotics), strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, erythromycin/clarithromycin, ritonavir) increase domperidone levels; drugs needing acidic pH for absorption (e.g., ketoconazole, atazanavir), warfarin (monitor), methotrexate (high-dose), digoxin
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep in original pack.
Pantop-D SR, Pan-D SR, Pantocid DSR, Pantodac DSR, Pansec DSR
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
At a glance
Good to know
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance.
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