Prescription requiredAnti-reflux/Anti-ulcerant (PPI + Prokinetic)

Neksium D 40/30MG Cap — Uses, Dosage & Benefits

Neksium D 40/30MG Cap is used for Gastroesophageal reflux disease (GERD), acid reflux/heartburn, gastritis and acidity with associated nausea/vomiting or bloating, functional dyspepsia.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

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Active Ingredient / Composition

Domperidone (30mg) + Esomeprazole (40mg)

What is Neksium D 40/30MG Cap used for?

Gastroesophageal reflux disease (GERD)
acid reflux/heartburn
gastritis and acidity with associated nausea/vomiting or bloating
functional dyspepsia

How Neksium D 40/30MG Cap Works

Esomeprazole is a proton pump inhibitor that reduces stomach acid by blocking the H+/K+ ATPase pump in gastric parietal cells. Domperidone is a dopamine (D2) receptor antagonist that increases gastric motility and helps relieve nausea and reflux by improving stomach emptying.

Dosage & Directions

Capsule (SR): take exactly as prescribed, usually once daily 30 minutes before food (preferably before breakfast). Swallow whole; do not crush, chew or open the capsule. If a dose is missed, take it when remembered unless it is near the next dose.

Always follow your doctor's prescription. Do not self-medicate.

Key Benefits

Relieves heartburn and acid reflux
Reduces stomach acid and heals esophagitis
Improves gastric emptying to reduce regurgitation/bloating
Helps control nausea and vomiting associated with reflux/dyspepsia

Pregnancy

Consult doctor (use with caution; domperidone generally avoided unless clearly needed)

Alcohol Interaction

Use with caution (alcohol can worsen acidity/GERD symptoms)

Neksium D 40/30MG Cap — Quick Facts

Composition: Domperidone (30mg) + Esomeprazole (40mg)
Therapeutic class: Anti-reflux/Anti-ulcerant (PPI + Prokinetic)
Drug class: Proton pump inhibitor (esomeprazole) + dopamine D2 antagonist prokinetic/antiemetic (domperidone)
Prescription: Required (Rx)
Price: ₹253
Habit forming: No
Storage: Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Neksium D 40/30MG Cap — Usage FAQs

How should I take this medicine?

Follow the dosage prescribed by your doctor. Do not alter the dose without medical advice.

Can I take this medicine without a prescription?

Prescription-required medicines need a valid Rx. OTC medicines can be purchased directly.

What if I miss a dose?

Take the missed dose as soon as you remember, unless it is close to your next scheduled dose. Do not double the dose.

How long does it take to show effect?

The time to show effect varies by medicine and condition. Consult your doctor for specific timelines.

Neksium D 40/30MG Cap — Uses, Dosage & Benefits

Active Ingredient / Composition

What is Neksium D 40/30MG Cap used for?

How Neksium D 40/30MG Cap Works

Dosage & Directions

Key Benefits

Pregnancy

Alcohol Interaction

Neksium D 40/30MG Cap — Quick Facts

Neksium D 40/30MG Cap — Usage FAQs

More from PingMeDoc™

Safety disclaimer

Neksium D 40/30MG Cap — Uses, Dosage & Benefits

Active Ingredient / Composition

What is Neksium D 40/30MG Cap used for?

How Neksium D 40/30MG Cap Works

Dosage & Directions

Key Benefits

Pregnancy

Alcohol Interaction

Neksium D 40/30MG Cap — Quick Facts

Neksium D 40/30MG Cap — Usage FAQs

More from PingMeDoc™

Safety disclaimer