Razo L

Composition of Razo L

Razo L contains Rabeprazole 20 mg + Levosulpiride 75 mg (SR). It belongs to the Proton pump inhibitor (Rabeprazole) + Dopamine D2 antagonist prokinetic (Levosulpiride) class of medicines.

Uses of Razo L

• Gastroesophageal reflux disease (GERD)
• acidity/heartburn
• erosive gastritis
• dyspepsia with nausea/bloating
• reflux associated with delayed gastric emptying

Key benefits

• Relieves heartburn and acid reflux
• Reduces stomach acid and heals gastritis/erosions
• Improves gastric emptying and bloating
• Helps nausea associated with dyspepsia

How Razo L works

Rabeprazole is a proton pump inhibitor that reduces stomach acid by blocking the H+/K+ ATPase in gastric parietal cells. Levosulpiride is a dopamine D2 antagonist with prokinetic and antiemetic action that improves gastric motility and reduces nausea, helping reflux symptoms.

How to take Razo L

Tablet/capsule for oral use. Usually taken once daily on an empty stomach, preferably 30 minutes before breakfast (as advised by doctor). Swallow whole; do not crush/chew sustained-release dosage forms.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause confusion, blurred vision, sweating and a fast heartbeat. It can cause drowsiness, disorientation and abnormal muscle movements. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Razo L

Most side effects of Razo L are mild and settle as the body adjusts. Reported side effects include:

• Headache
• dizziness
• diarrhea
• constipation
• abdominal pain
• nausea
• flatulence
• dry mouth
• sleepiness
• restlessness
• increased prolactin (breast tenderness/galactorrhea)
• rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Razo L

Warnings and precautions

Use only on medical advice. Prolonged PPI use may cause low magnesium, vitamin B12 deficiency, increased fracture risk, and risk of C. difficile diarrhea; seek care for persistent diarrhea. Levosulpiride may cause extrapyramidal symptoms (tremor, rigidity), drowsiness, and hyperprolactinemia (menstrual irregularities, breast changes); avoid driving if sleepy. Use with caution in liver/kidney impairment, elderly, history of seizures, Parkinson’s disease, prolactin-dependent tumors, or QT prolongation/arrhythmia. Get evaluated for alarm symptoms (weight loss, GI bleeding, persistent vomiting, difficulty swallowing) before use.

Do not take Razo L if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Antacids may reduce absorption if taken together (separate dosing). Drugs needing acidic pH for absorption (e.g., ketoconazole/itraconazole/posaconazole, atazanavir) may be affected by rabeprazole. Warfarin (monitor INR), digoxin (monitor levels), methotrexate (high-dose) interaction possible with PPIs. Levosulpiride: additive CNS depression with alcohol/sedatives, increased risk of QT prolongation with macrolides/fluoroquinolones/antipsychotics, antagonizes dopamine agonists (levodopa), caution with other antipsychotics and serotonergic antiemetics.

How to store Razo L

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack and out of reach of children.

Expert advice for Razo L

Take it before breakfast, not after a meal. Eat smaller meals, avoid late dinners, raise the head of your bed and avoid smoking — these do as much as the tablet for reflux. Take it shortly before meals for bloating and early fullness. Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting.

Manufacturer and class

Manufacturer:

DR.REDDYS

Therapeutic class:

Antiulcer/Anti-reflux (PPI + Prokinetic)

Drug class:

Proton pump inhibitor (Rabeprazole) + Dopamine D2 antagonist prokinetic (Levosulpiride)