Prescription requiredAntidiabetic

Ziomet Life 50/500 Tab — Side Effects & Warnings

Known side effects of Ziomet Life 50/500 Tab include Nausea, diarrhoea, abdominal discomfort, loss of appetite, metallic taste, headache, upper respiratory tract infection, hypoglycaemia (especially with insulin/sulfonylureas), dizziness. Not everyone experiences these side effects.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026

Common Side Effects

Nausea
diarrhoea
abdominal discomfort
loss of appetite
metallic taste
headache
upper respiratory tract infection
hypoglycaemia (especially with insulin/sulfonylureas)
dizziness

This is not an exhaustive list. Consult your doctor if you notice any unusual symptoms.

Important Warnings

Prescription-only. Monitor kidney function before and during therapy; metformin is contraindicated in severe renal impairment and should be used with caution in reduced eGFR. Risk of lactic acidosis (rare but serious), higher with kidney disease, dehydration, severe infection, hypoxia, liver disease, heavy alcohol use; stop and seek urgent care if rapid breathing, severe weakness, abdominal pain occur. Temporarily stop metformin around iodinated contrast procedures and major surgery as advised. Sitagliptin may rarely cause pancreatitis and severe joint pain; discontinue and consult doctor if severe abdominal pain. Monitor for hypersensitivity reactions and signs of heart failure in susceptible patients.

Drug Interactions

Ziomet Life 50/500 Tab may interact with the following:

Alcohol (increases lactic acidosis risk)
iodinated contrast media (temporary interruption)
carbonic anhydrase inhibitors e.g. topiramate/acetazolamide (increases metabolic acidosis risk)
cationic drugs affecting renal tubular secretion (e.g. cimetidine)
insulin and sulfonylureas (increased hypoglycaemia risk; dose adjustment may be needed)
diuretics/ACE inhibitors/NSAIDs (may affect renal function)
digoxin (sitagliptin may slightly increase digoxin levels)

Always tell your doctor about all medicines you are taking, including over-the-counter drugs and supplements.

Pregnancy Safety

Consult doctor

Alcohol Interaction

Avoid

Habit Forming

Storage

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

Ziomet Life 50/500 Tab — Safety Summary

Composition: Sitagliptin 50 mg + Metformin 500 mg (as Metformin Hydrochloride)
Prescription: Required (Rx)
Pregnancy: Consult doctor
Alcohol: Avoid
Habit forming: No

Ziomet Life 50/500 Tab — Safety FAQs

What should I do if I experience side effects?

Mild side effects often resolve on their own. If side effects are severe or persistent, stop the medicine and consult your doctor immediately.

Are all listed side effects common?

No. Some side effects are common while others are rare. Not everyone experiences side effects. Consult your doctor if you are concerned.

Can I take this medicine with other drugs?

Some medicines interact with each other. Always inform your doctor about all medicines you are currently taking.

When should I seek emergency help?

Seek immediate medical attention if you experience severe allergic reactions (difficulty breathing, swelling of face/throat), chest pain, or any life-threatening symptoms.

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Safety disclaimer

This information is for educational purposes only and is not a substitute for professional medical advice. If you experience severe side effects, seek medical attention immediately.

Ziomet Life 50/500 Tab — Side Effects & Warnings

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated June 2026