Zofer Syrup

Composition

Ondansetron (2mg/5ml)

Uses of Zofer Syrup

Prevention and treatment of nausea and vomiting due to chemotherapy, radiotherapy, or surgery (post-operative nausea/vomiting); may be used for other causes of vomiting as advised by a doctor

• •Relieves nausea
• •Controls vomiting
• •Useful in chemo/radiotherapy-induced nausea
• •Helps prevent post-operative nausea and vomiting

How it works

Ondansetron is a selective 5-HT3 (serotonin) receptor antagonist. It blocks serotonin receptors in the gut and in the brain’s vomiting center, thereby reducing nausea and vomiting.

Directions for use

Oral syrup: take the measured dose using a measuring cup/spoon as prescribed. Can be taken with or without food; if nausea persists, take at the times advised by the doctor (often before chemotherapy/radiotherapy or as needed post-operatively). Do not exceed the prescribed dose.

Side effects

Common side effects of Zofer Syrup may include:

• •Headache
• •constipation
• •diarrhoea
• •dizziness
• •fatigue
• •flushing

Warnings & precautions

Use with caution in patients with heart rhythm problems (QT prolongation), heart failure, bradycardia, electrolyte imbalance (low potassium/magnesium), and severe liver impairment (dose adjustment may be needed). Seek medical help if palpitations, fainting, severe dizziness, allergic reaction, or symptoms of serotonin syndrome occur (agitation, fever, sweating, tremor). Not a substitute for evaluation of persistent vomiting or dehydration, especially in children.