Zofer Syrup

Composition of Zofer Syrup

Zofer Syrup contains Ondansetron (2mg/5ml). It belongs to the 5-HT3 receptor antagonist class of medicines.

Uses of Zofer Syrup

• Prevention and treatment of nausea and vomiting due to chemotherapy
• radiotherapy
• or surgery (post-operative nausea/vomiting); may be used for other causes of vomiting as advised by a doctor

Key benefits

• Relieves nausea
• Controls vomiting
• Useful in chemo/radiotherapy-induced nausea
• Helps prevent post-operative nausea and vomiting

How Zofer Syrup works

Ondansetron is a selective 5-HT3 (serotonin) receptor antagonist. It blocks serotonin receptors in the gut and in the brain’s vomiting center, thereby reducing nausea and vomiting.

How to take Zofer Syrup

Oral syrup: take the measured dose using a measuring cup/spoon as prescribed. Can be taken with or without food; if nausea persists, take at the times advised by the doctor (often before chemotherapy/radiotherapy or as needed post-operatively). Do not exceed the prescribed dose.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zofer Syrup

Most side effects of Zofer are mild and settle as the body adjusts. Reported side effects include:

• Headache
• constipation
• diarrhoea
• dizziness
• fatigue
• flushing

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zofer Syrup

Warnings and precautions

Use with caution in patients with heart rhythm problems (QT prolongation), heart failure, bradycardia, electrolyte imbalance (low potassium/magnesium), and severe liver impairment (dose adjustment may be needed). Seek medical help if palpitations, fainting, severe dizziness, allergic reaction, or symptoms of serotonin syndrome occur (agitation, fever, sweating, tremor). Not a substitute for evaluation of persistent vomiting or dehydration, especially in children.

Do not take Zofer if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Apomorphine (contraindicated), other QT-prolonging drugs (e.g., amiodarone, sotalol, certain antipsychotics/macrolides/fluoroquinolones), serotonergic drugs (SSRIs/SNRIs, MAOIs, linezolid, tramadol) increased serotonin syndrome risk, strong CYP3A4 inducers (rifampicin, carbamazepine, phenytoin) may reduce effect

How to store Zofer Syrup

Store below 25°C in a cool, dry place. Protect from light and moisture. Keep bottle tightly closed and out of reach of children.

Expert advice for Zofer Syrup

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed Zofer Syrup for prevention of nausea and vomiting caused by chemotherapy, radiotherapy and after surgery.</li> <li>Unlike some other nausea medicines, the side effects for Zofer Syrup are relatively mild.</li> <li>It comes in many different forms that you don't have to swallow, such as a film that goes on the tongue or a dissolving pill.</li> <li>It is fast-acting and starts working within 30 minutes.</li> <li>If you vomit within one hour of taking a dose, take another dose.</li> <li>Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:

SUN PHARMA 2

Therapeutic class:

Antiemetic

Drug class:

5-HT3 receptor antagonist