Ondem Syrup

Composition of Ondem Syrup

Ondem Syrup contains Ondansetron (2mg/5ml). It belongs to the 5-HT3 receptor antagonist (serotonin antagonist) class of medicines.

Uses of Ondem Syrup

• Prevention and treatment of nausea and vomiting due to chemotherapy
• radiotherapy
• and post-operative states; doctor may also prescribe for severe vomiting due to other causes.

Key benefits

• Controls nausea and vomiting
• Helpful in chemotherapy-induced vomiting
• Useful for post-operative nausea
• Improves oral intake and hydration by reducing vomiting

How Ondem Syrup works

Ondansetron is a selective 5-HT3 (serotonin) receptor antagonist. It blocks serotonin receptors in the gut and the vomiting center in the brain, reducing the nausea and vomiting reflex.

How to take Ondem Syrup

Oral syrup. Shake well before use and measure with a calibrated spoon/cup. Take exactly as prescribed; can be taken with or without food. Dose depends on age/weight and the cause of vomiting; do not exceed the prescribed frequency.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Ondem Syrup

Most side effects of Ondem are mild and settle as the body adjusts. Reported side effects include:

• Headache
• constipation
• diarrhea
• dizziness
• fatigue
• flushing
• dry mouth

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Ondem Syrup

Warnings and precautions

Prescription (Schedule H) medicine. Use with caution in patients with heart rhythm disorders, congenital long QT syndrome, bradyarrhythmias, electrolyte disturbances (low potassium/magnesium), or those taking other QT-prolonging drugs. Seek medical help for palpitations, fainting, severe dizziness, or signs of allergic reaction. Use caution in liver impairment (may need dose adjustment). Not for self-treatment of persistent vomiting—evaluate dehydration and underlying cause, especially in children.

Do not take Ondem if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

QT-prolonging medicines (e.g., amiodarone, sotalol, certain antipsychotics and antibiotics like macrolides/fluoroquinolones), serotonergic drugs (SSRIs/SNRIs, tramadol, linezolid) due to serotonin syndrome risk, apomorphine (contraindicated—severe hypotension/loss of consciousness), strong CYP3A4 inducers (e.g., rifampicin, phenytoin, carbamazepine) may reduce effect

How to store Ondem Syrup

Store below 25°C, protected from light and moisture. Keep bottle tightly closed. Do not freeze. Keep out of reach of children.

Expert advice for Ondem Syrup

Ondem Syrup effectively controls nausea and bouts of vomiting reflex in children undergoing chemotherapy or radiotherapy sessions. It is fast-acting and starts working within 30 minutes. Practice self-care measures: Give plenty of fluids to your child to avoid dehydration Avoid giving fried and spicy food or heavy meals to your child. Ensure that your child eats slowly and in small proportions.

Manufacturer and class

Manufacturer:

ALKEM LAB

Therapeutic class:

Antiemetic

Drug class:

5-HT3 receptor antagonist (serotonin antagonist)

Chemical class:

Carbazoles