Drug | Tablet

Treatment of hypertension (high blood pressure); may be used when single-drug therapy is insufficient to control BP.

Atenolol is a selective beta-1 blocker that slows heart rate and reduces the force of contraction, lowering cardiac output and blood pressure. Chlorthalidone is a thiazide-like diuretic that increases salt and water excretion from the kidneys, reducing blood volume and peripheral resistance.

Oral tablet. Take exactly as prescribed, usually once daily at the same time each day, with or without food. Do not stop suddenly without medical advice; if a dose is missed, take it when remembered unless it is close to the next dose.

Dizziness, fatigue, slow heart rate (bradycardia), low blood pressure, headache, cold extremities, nausea, increased urination, electrolyte imbalance (low potassium/low sodium), increased uric acid, increased blood sugar

Use with caution in asthma/COPD (may worsen bronchospasm), diabetes (may mask hypoglycaemia symptoms), thyroid disease (may mask thyrotoxicosis), peripheral vascular disease, and in the elderly. Avoid abrupt discontinuation (risk of angina/arrhythmias). Monitor BP, pulse, kidney function, and electrolytes (especially potassium and sodium). Use caution in kidney impairment and in patients with gout/hyperuricaemia. Not recommended in severe bradycardia, 2nd/3rd degree heart block, cardiogenic shock, severe uncontrolled heart failure, or severe hypotension unless directed by a physician.

Other antihypertensives (additive hypotension), verapamil/diltiazem/amiodarone/digoxin (increased risk of bradycardia/heart block), clonidine (rebound hypertension on withdrawal), NSAIDs (reduced antihypertensive/diuretic effect), lithium (increased lithium levels/toxicity), insulin/oral antidiabetics (masked hypoglycaemia), corticosteroids and amphotericin B (increased risk of hypokalaemia), alcohol (increased dizziness), ACE inhibitors/ARBs (additive BP lowering, monitor potassium/renal function)

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Aten 25 Plus Tablet, Atenolol+Chlorthalidone 25/12.5 Tablet (generic), Tenolol CH 25 Tablet, Betaclor 25 Tablet, Atenolol CT 25 Tablet