Empadon-M 25/1000 mg ER Tablet

Composition of Empadon-M 25/1000 mg ER Tablet

Empadon-M 25/1000 mg ER Tablet contains Empagliflozin 25 mg + Metformin Hydrochloride 1000 mg (Extended Release). It belongs to the SGLT2 inhibitor + Biguanide (Metformin ER) class of medicines.

Uses of Empadon-M 25/1000 mg ER Tablet

Type 2 diabetes mellitus (as an adjunct to diet and exercise) to improve glycaemic control; helps reduce risk of diabetes-related complications as advised by physician

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves insulin sensitivity and reduces liver glucose output
• Promotes glucose loss through urine leading to modest weight reduction
• Lowers blood pressure mildly in some patients
• Once-daily ER formulation may improve tolerance and adherence

How Empadon-M 25/1000 mg ER Tablet works

Empagliflozin is an SGLT2 inhibitor that lowers blood sugar by increasing urinary glucose excretion through the kidneys. Metformin (ER) reduces glucose production in the liver and improves insulin sensitivity, helping the body use insulin better.

How to take Empadon-M 25/1000 mg ER Tablet

Oral extended-release tablet. Take exactly as prescribed, usually once daily with the evening meal or with food to reduce stomach upset. Swallow whole; do not crush, break, or chew. Maintain adequate hydration and follow diet/exercise advice; monitor blood glucose.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take the missed dose of Empadon-M 25/1000 mg ER as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.

If you take too much

Taking more Empadon-M 25/1000 mg ER than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Empadon-M 25/1000 mg ER Tablet

Most side effects of Empadon-M 25/1000 mg ER are mild and settle as the body adjusts. Reported side effects include:

• Genital fungal infection
• urinary tract infection
• increased urination
• thirst
• nausea
• diarrhoea
• abdominal discomfort
• headache
• dizziness
• reduced appetite

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Empadon-M 25/1000 mg ER Tablet

Warnings and precautions

For Type 2 diabetes only (not for Type 1 diabetes or diabetic ketoacidosis). Risk of lactic acidosis with metformin—higher in severe kidney disease, dehydration, heavy alcohol use, liver disease, or hypoxia; stop and seek urgent care for rapid breathing, severe weakness, abdominal pain. Empagliflozin can cause dehydration/low BP, ketoacidosis (even with near-normal sugars), serious genital infections (Fournier’s gangrene), and increased risk of urinary/genital infections. Assess kidney function before and during therapy; avoid in severe renal impairment (eGFR thresholds per prescriber). Temporarily stop before major surgery or during acute illness with reduced intake/fluids. Use caution in elderly and those on diuretics. Consider vitamin B12 monitoring with long-term metformin.

Interactions with other medicines

Diuretics (increased dehydration/hypotension), insulin or sulfonylureas (increased hypoglycaemia risk), ACE inhibitors/ARBs (may enhance BP lowering), NSAIDs and iodinated contrast (may worsen kidney function and increase lactic acidosis risk), carbonic anhydrase inhibitors e.g., topiramate (metabolic acidosis risk), cimetidine (increases metformin levels), alcohol (increases lactic acidosis risk), digoxin (empagliflozin may increase levels slightly)

How to store Empadon-M 25/1000 mg ER Tablet

Store below 25°C in a dry place, protected from moisture and direct light. Keep in original blister pack and out of reach of children.

Manufacturer and class

Manufacturer:

CADILA PHARMA

Therapeutic class:

Antidiabetic

Drug class:

SGLT2 inhibitor + Biguanide (Metformin ER)