Sitared Md Ir 1000 Tablet

Composition of Sitared Md Ir 1000 Tablet

Sitared Md Ir 1000 Tablet contains Dapagliflozin (5mg) + Metformin (500mg) + Sitagliptin (50mg). It belongs to the DPP-4 inhibitor + Biguanide class of medicines.

Uses of Sitared Md Ir 1000 Tablet

Type 2 diabetes mellitus: adjunct to diet and exercise to improve glycaemic control in adults when metformin/sitagliptin alone is inadequate or as replacement therapy.

Key benefits

• Lowers fasting and post-meal blood sugar
• Improves HbA1c control
• Helps reduce insulin resistance
• Low risk of hypoglycaemia when used without insulin/secretagogues
• Convenient combination therapy

How Sitared Md Ir 1000 Tablet works

Sitagliptin is a DPP-4 inhibitor that increases incretin hormones (GLP-1, GIP), enhancing glucose-dependent insulin release and reducing glucagon. Metformin decreases hepatic glucose production and improves peripheral insulin sensitivity, lowering blood glucose without usually causing hypoglycaemia alone.

How to take Sitared Md Ir 1000 Tablet

Take as prescribed by physician. Usually taken with or after meals to reduce stomach upset. Place the MD tablet on the tongue to dissolve and swallow (with/without water). Do not crush/chew unless advised; follow dose adjustments based on kidney function and blood glucose.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Sitared-MD XR 1000 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

Taking more Sitared Md Ir than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.

Side effects of Sitared Md Ir 1000 Tablet

Most side effects of Sitared Md Ir are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhoea
• abdominal discomfort
• loss of appetite
• headache
• dizziness
• upper respiratory tract infection
• hypoglycaemia (more likely with insulin/sulfonylureas)
• taste disturbance

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Sitared Md Ir 1000 Tablet

Warnings and precautions

Not for type 1 diabetes or diabetic ketoacidosis. Metformin may rarely cause lactic acidosis—risk increases with kidney disease, dehydration, severe infection, alcohol misuse, heart failure, liver disease, or low oxygen states; stop and seek urgent care if deep/rapid breathing, severe weakness, abdominal pain occur. Use caution/avoid if eGFR is significantly reduced; monitor renal function periodically. Temporarily stop metformin around iodinated contrast studies or major surgery as advised. Sitagliptin has been associated rarely with pancreatitis and severe joint pain; stop and consult doctor if severe abdominal pain. Monitor for allergic reactions and bullous pemphigoid symptoms.

Interactions with other medicines

Alcohol (increases lactic acidosis risk), iodinated contrast media, carbonic anhydrase inhibitors (e.g., topiramate, acetazolamide), cimetidine, diuretics, corticosteroids, thyroid hormones, sympathomimetics, antipsychotics (may raise glucose), ACE inhibitors (may enhance glucose-lowering), insulin/sulfonylureas (increased hypoglycaemia risk), digoxin (sitagliptin may increase levels)

How to store Sitared Md Ir 1000 Tablet

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack and out of reach of children.

Expert advice for Sitared Md Ir 1000 Tablet

Your doctor will monitor your blood sugar levels and kidney function regularly while you are taking this medication. Hypoglycemia (low blood sugar level) may occur when Sitared-MD XR 1000 Tablet is taken along with other antidiabetic medicines, alcohol, or when delaying/skipping a meal. Check your blood sugar levels and have a snack/sugar source for immediate relief. If you get unusually thirsty, pass urine more frequently, or feel tired, let your doctor know. These are signs that there is too much sugar in your blood, and your dose may need adjusting. Lifestyle changes, like a low-fat and salt diet, exercise, not smoking, and cutting down on the amount of alcohol you normally drink, may help this medicine work better.

Manufacturer and class

Manufacturer:

SUN PHARMA 2

Therapeutic class:

Antidiabetic

Drug class:

DPP-4 inhibitor + Biguanide