Glimefort-M2 Tab

Tablet

Type 2 diabetes mellitus (adult) to control high blood sugar when diet and exercise alone are not sufficient

Glimepiride (a sulfonylurea) increases insulin release from the pancreas. Metformin (a biguanide) reduces glucose production in the liver and improves insulin sensitivity, helping the body use glucose better.

Oral tablet. Take exactly as prescribed, usually once daily with/after a main meal (preferably breakfast). Swallow whole; do not crush/chew if modified/extended-release. Monitor blood glucose regularly and follow diet/exercise advice.

Hypoglycaemia (low blood sugar),nausea,diarrhoea,abdominal discomfort,metallic taste,headache,dizziness,weight gain

Prescription-only antidiabetic. Risk of hypoglycaemia (especially with missed meals, alcohol, heavy exercise, or with other antidiabetics); carry glucose. Metformin may rarely cause lactic acidosis—risk higher in kidney impairment, dehydration, severe infection, heart/respiratory failure, alcohol use; assess renal function before and during therapy. Hold metformin before/after iodinated contrast procedures and major surgery as advised. Use caution in elderly and in liver disease. Not for type 1 diabetes or diabetic ketoacidosis.

Alcohol (increases hypoglycaemia and lactic acidosis risk),insulin/other antidiabetics (additive hypoglycaemia),ACE inhibitors (may enhance glucose-lowering),beta-blockers (mask hypoglycaemia symptoms),corticosteroids/thiazide diuretics/sympathomimetics (raise blood glucose),rifampicin (reduces glimepiride effect),fluconazole/azoles (increase sulfonylurea effect),iodinated contrast media (metformin—lactic acidosis risk)

Store below 25°C in a cool, dry place. Protect from moisture and direct light. Keep out of reach of children.

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