Beta-2 Microglobulin Test (B2M)

Beta 2 Microglobulin Test: quick answers

Beta 2 Microglobulin Test price

₹1,199, home sample collection

Normal range (adults)

Adults with normal kidney function: roughly 1 to 2.5 mg/L (method dependent)

Done for

Staging multiple myeloma at diagnosis; Assessing outlook in chronic lymphocytic leukaemia and some lymphomas; Monitoring response to treatment in these conditions

Fasting

Not required

Report

Same day / 24 hours

What is the Beta 2 Microglobulin Test?

Beta-2 microglobulin (B2M) is a small protein found on the surface of most cells and in the blood. Its level rises when certain blood cancers are active and when the kidneys filter less well. Doctors mainly use it to stage and follow multiple myeloma and some lymphomas and leukaemias.

Beta 2 Microglobulin Test normal range

Ranges differ between methods and rise with age and with reduced kidney function. In myeloma staging, values below 3.5 mg/L and 5.5 mg/L or above are the standard cut-offs.

Ranges differ between laboratories and methods. The reference range printed on your own report is the one to read your result against.

What your Beta 2 Microglobulin Test result means

High B2M

Can reflect a larger amount of disease in myeloma, lymphoma or leukaemia, or reduced kidney function. It can also rise with some infections and autoimmune conditions. It is not a screening test for cancer.

In multiple myeloma

Under the International Staging System, B2M below 3.5 mg/L with albumin at least 3.5 g/dL is stage I, and B2M of 5.5 mg/L or more is stage III. The treating haematologist explains what the stage means.

One result is not a diagnosis. A doctor reads it with your symptoms, history, medicines and other tests.

Why is the Beta 2 Microglobulin Test done?

• Staging multiple myeloma at diagnosis
• Assessing outlook in chronic lymphocytic leukaemia and some lymphomas
• Monitoring response to treatment in these conditions
• Occasionally, assessing kidney tubule damage

What does the Beta-2 Microglobulin Test (B2M) measure?

1 parameter. Expand a group to see the measurements, units and available method details.

The reference interval printed on your actual laboratory report governs interpretation. Intervals can vary by laboratory, method, age, sex and pregnancy. Methods can also vary by processing laboratory.

Beta 2 Microglobulin Test: sample & preparation

Sample: Blood. Fasting: Not required.

• No fasting is required. Tell the lab if you have kidney disease, since reduced kidney function raises this result independent of the condition being investigated.

Frequently asked questions