
Laboratory test
Coagulation Profile Test (Clotting Profile: PT, INR, aPTT)
Coagulation Profile: 6 parameters from a blood sample, no fasting.
Also known as
Coagulation Profile Test · Clotting Profile · Coag Profile · Coagulation Profile Blood Test · PT INR aPTT Test · Bleeding and Clotting Tests · PT INR aPTT test · Clotting profile
- Sample
- Blood
- Fasting
- Not required
- Expected report time
- Same day / 24 hours
- Parameters
- 6
Coagulation Profile Test: quick answers
- Coagulation Profile Test full form
- Coagulation Profile
- Coagulation Profile Test price
- ₹749, home sample collection
- Normal range (adults)
- PT (prothrombin time): About 11 to 13.5 seconds; INR (not on warfarin): About 0.8 to 1.2 more
- Done for
- Before surgery, a biopsy or a dental or other procedure; Easy bruising, nosebleeds, heavy periods or bleeding that is hard to stop; Monitoring warfarin treatment (PT and INR)
- Fasting
- Not required
- Report
- Same day / 24 hours
What is the Coagulation Profile Test?
A coagulation profile is a set of blood tests that shows how well your blood clots. It usually includes PT with INR and aPTT, and sometimes fibrinogen and thrombin time. Doctors order it before surgery, for unexplained bleeding or bruising, and to monitor blood thinners.
Coagulation Profile Test normal range
| Measurement | Typical adult value |
|---|---|
| PT (prothrombin time) | About 11 to 13.5 seconds |
| INR (not on warfarin) | About 0.8 to 1.2 |
| INR on warfarin (most conditions) | Usually targeted at 2.0 to 3.0 |
| aPTT | About 25 to 35 seconds |
| Fibrinogen | About 200 to 400 mg/dL |
Clotting times depend on the reagent and the analyser, so each lab sets its own range and the aPTT range in particular varies between labs. Use the range printed on your report. A warfarin target is set by your doctor for your condition.
Ranges differ between laboratories and methods. The reference range printed on your own report is the one to read your result against.
What your Coagulation Profile Test result means
- Prolonged PT or raised INR
- Blood is taking longer to clot. Common reasons are warfarin treatment, liver disease and vitamin K deficiency. A doctor decides what it means in your case.
- Prolonged aPTT
- Can go with heparin treatment, a deficiency of a clotting factor such as in haemophilia, or some antibodies. The doctor may repeat or add tests to find the cause.
- Low fibrinogen
- Fibrinogen is used up or made less in conditions such as severe liver disease or widespread clotting problems. It is interpreted with the other results.
- All within range
- The main clotting pathways are working in this test. Some bleeding disorders, such as certain platelet or von Willebrand disorders, can still have a normal profile.
One result is not a diagnosis. A doctor reads it with your symptoms, history, medicines and other tests.
Why is the Coagulation Profile Test done?
- Before surgery, a biopsy or a dental or other procedure
- Easy bruising, nosebleeds, heavy periods or bleeding that is hard to stop
- Monitoring warfarin treatment (PT and INR)
- Liver disease, where clotting factors can fall
- Unexplained blood clots or repeated miscarriage, as part of a wider work-up
What does the Coagulation Profile Test (Clotting Profile: PT, INR, aPTT) measure?
6 parameters. Expand a group to see the measurements, units and available method details.
Other measurements6 parameters
| Parameter | Unit | LOINC |
|---|---|---|
| Prothrombin Time (PT) | sec | 5902-2 |
| International Normalised Ratio (INR) | ratio | 6301-6 |
| Activated Partial Thromboplastin Time (APTT) | sec | 14979-9 |
| Bleeding Time + Clotting Time | min | |
| Bleeding Time (BT) | min | |
| Clotting Time (CT) | min |
The reference interval printed on your actual laboratory report governs interpretation. Intervals can vary by laboratory, method, age, sex and pregnancy. Methods can also vary by processing laboratory.
Coagulation Profile Test: sample & preparation
Sample: Blood. Fasting: Not required.
- No fasting is required. Tell the lab if you are taking any blood-thinning medicine (such as warfarin, heparin, or aspirin), as this affects the results.
Frequently asked questions
What tests are in a coagulation profile?
What is the normal range for a coagulation profile?
Is a coagulation profile the same as a clotting profile?
Do I need to stop medicines before a coagulation profile?
Is fasting needed for a coagulation profile?
How much does the Coagulation Profile cost?
Can I book this test for home collection?
When is the report expected?
Can I book this with other tests?
Sources: Dacie and Lewis Practical Haematology, 12th edition; Tietz Textbook of Clinical Chemistry and Molecular Diagnostics; British Society for Haematology guidelines on oral anticoagulation with warfarin. General information, not medical advice.
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6 parameters · No fasting required · Report time: Same day / 24 hours
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