
Adaferin Gel
Galderma India Pvt Ltd - Gel - 0.1%W/W - 15 G
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Biluma Advance Day Cream is used for hyperpigmentation, melasma, dark spots, uneven skin tone; day-time skin brightening and photoprotection support (product-dependent).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Skin brightening creams typically work by reducing excess melanin formation and promoting even skin tone using depigmenting and antioxidant ingredients. Day creams may also hydrate the skin barrier and may include UV filters to reduce tanning and recurrence of spots.
Apply a thin layer to clean, dry face and neck in the morning. Use sunscreen on top if the product does not provide adequate SPF; reapply sunscreen as needed. Avoid contact with eyes and broken skin.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take the missed dose of Biluma Advance Day as soon as you remember. If it is almost time for the next dose, skip the missed one and carry on with the usual schedule. Do not take two doses together to make up for a missed dose.
Taking more Biluma Advance Day than prescribed can be harmful. If you suspect an overdose, contact a doctor or go to the nearest emergency department at once, and carry the pack or strip with you. In India the emergency number is 112.
Most side effects of Biluma Advance Day are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Alcohol | No known interaction |
| Habit forming | No |
Patch test before first use. Stop use if severe irritation, swelling, or rash occurs. Avoid using with strong exfoliants/retinoids initially if sensitive. If pregnant/breastfeeding or under dermatology treatment, consult a dermatologist before use.
May increase irritation when used with retinoids, AHAs/BHAs, benzoyl peroxide or other depigmenting agents; if combining, introduce gradually and use sunscreen.
Store at room temperature below 30°C, away from heat and direct sunlight. Keep cap tightly closed.

Galderma India Pvt Ltd - Gel - 0.1%W/W - 15 G
Save ₹18
Prescription required

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The information on Biluma Advance Day Cream is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.