Duloxee 40 Tablet

Composition of Duloxee 40 Tablet

Duloxee 40 Tablet contains Duloxetine 40 mg (as hydrochloride) tablets. It belongs to the SNRI (Serotonin-Norepinephrine Reuptake Inhibitor) class of medicines.

Uses of Duloxee 40 Tablet

• Treatment of major depressive disorder
• generalized anxiety disorder
• diabetic peripheral neuropathic pain
• fibromyalgia
• and chronic musculoskeletal pain (as prescribed).

Key benefits

• Helps relieve depression symptoms
• reduces anxiety symptoms
• reduces neuropathic pain
• improves chronic pain conditions
• may improve overall functioning and quality of life

How Duloxee 40 Tablet works

Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI). It increases serotonin and noradrenaline levels in the brain and spinal cord, improving mood and reducing pain signal transmission.

How to take Duloxee 40 Tablet

Take by mouth as directed by the physician, preferably at the same time each day. Can be taken with or without food; swallow tablet whole with water. Do not stop suddenly without medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Duloxee 40 Tablet

Most side effects of Duloxee are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• dry mouth
• dizziness
• sleepiness
• insomnia
• constipation
• decreased appetite
• sweating
• fatigue
• headache

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Duloxee 40 Tablet

Warnings and precautions

Prescription-only medicine. Do not use with MAO inhibitors or within 14 days of stopping an MAOI; risk of serotonin syndrome. Use with caution in liver disease, severe kidney disease, uncontrolled hypertension, seizure disorders, bipolar disorder/mania, glaucoma, and in elderly (fall risk). Monitor for suicidal thoughts especially at treatment start or dose changes. May cause withdrawal symptoms if stopped abruptly. Can increase bleeding risk when combined with NSAIDs/anticoagulants. Not recommended in severe hepatic impairment.

Do not take Duloxee if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.

Interactions with other medicines

MAO inhibitors (contraindicated), other serotonergic drugs (SSRIs/SNRIs/triptans/linezolid/lithium) and tramadol (serotonin syndrome), CYP1A2 inhibitors (fluvoxamine, ciprofloxacin) may increase levels, CYP2D6 inhibitors/substrates (paroxetine, quinidine, some antipsychotics) interactions, anticoagulants/antiplatelets/NSAIDs (bleeding risk), alcohol (liver/CNS risk)

How to store Duloxee 40 Tablet

Store below 25°C in a cool, dry place away from light and moisture. Keep out of reach of children.

Expert advice for Duloxee 40 Tablet

Give it a fair trial of several weeks, and keep your review appointments. Take it at the same time each day — at night if it makes you drowsy, in the morning if it disturbs sleep. Talking therapy alongside medicine works better than either alone for most people.

Manufacturer and class

Manufacturer:

TALENT INDIA

Therapeutic class:

Antidepressant / Neuropathic pain agent

Drug class:

SNRI (Serotonin-Norepinephrine Reuptake Inhibitor)