OTC · No prescriptionSodium hyaluronate 0.15% w/v, Polyethylene glycol 400 0.4% w

Systane Hydration 10 ml, Substitutes & Alternatives

Find medicines with the same composition as Systane Hydration 10 ml (Sodium hyaluronate 0.15% w/v, Polyethylene glycol 400 0.4% w/v, Propylene glycol 0.3% w/v (lubricating eye drops)). Compare alternatives at different price points.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Known Substitutes

The following medicines may be used as alternatives to Systane Hydration 10 ml (same or similar composition):

Hylo-Comod Eye Drops (Sodium Hyaluronate 0.1%)
Hyalugel Eye Drops (Sodium Hyaluronate)
Refresh Tears Eye Drops (Carboxymethylcellulose)
Systane Ultra Eye Drops
Optive Eye Drops (Carboxymethylcellulose + Glycerin)

Important: Never switch medicines without consulting your doctor or pharmacist. Even medicines with the same composition may have different inactive ingredients that affect how they work for you.

Understanding the Composition

Systane Hydration 10 ml contains Sodium hyaluronate 0.15% w/v, Polyethylene glycol 400 0.4% w/v, Propylene glycol 0.3% w/v (lubricating eye drops). Substitute medicines with the same active ingredient work by the same mechanism and treat the same conditions.

Price differences between brands are common and do not indicate a difference in quality or effectiveness. All medicines sold in India must meet the standards set by CDSCO (Central Drugs Standard Control Organisation).

Available Alternatives on PingMeDoc™

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5% off

Refresh Tears

Allergan India Pvt Ltd - 10 ml

₹126₹132

Save ₹6

10% off

Refresh Tears Eye Drops

Allergan India Pvt Ltd - Drop - 10 ml

₹124₹138

Save ₹14

Systane Hydration 10 ml: At a Glance

Composition: Sodium hyaluronate 0.15% w/v, Polyethylene glycol 400 0.4% w/v, Propylene glycol 0.3% w/v (lubricating eye drops)
Price: ₹603
Prescription: Not required (OTC)
Manufacturer: ALCON INDIA
Known substitutes: 5

Systane Hydration 10 ml: Substitute FAQs

Are substitutes as effective as the original medicine?

Substitutes with the same active ingredient (salt) work in a similar way. However, inactive ingredients may differ. Always consult your doctor before switching.

Why are some substitutes cheaper?

Generic medicines are usually cheaper because manufacturers don't have the same development costs as the original brand. They contain the same active ingredient in the same strength.

Can I switch to a substitute on my own?

No. Always consult your doctor or pharmacist before switching medicines, even if the substitute has the same composition.

What is the difference between generic and branded medicines?

Generic medicines contain the same active ingredients as branded ones but are sold under different names, often at lower prices. Both are regulated for safety and efficacy.