OTC · No prescriptionSodium hyaluronate 0.15% w/v (Preservative-free lubricant ey

Systane Hydration Pf, Substitutes & Alternatives

Find medicines with the same composition as Systane Hydration Pf (Sodium hyaluronate 0.15% w/v (Preservative-free lubricant eye drops)). Compare alternatives at different price points.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹760MRP ~~₹800~~In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

Not sure whether to switch? Speak to a registered doctor.

Same salt, lower price

Medicines with the same active ingredient and strength as Systane Hydration Pf.

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Systane Hydration Pf

10 ml

₹760

₹76.00 per ml

Systane Hydration 10ML
ALCON INDIA · 10 ml - 10 ml
₹603
₹60.33 per ml
Save 21%

Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Systane Hydration Pf. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Known Substitutes

The following medicines may be used as alternatives to Systane Hydration Pf (same or similar composition):

Hylo-Comod Eye Drops (0.1% sodium hyaluronate)
Hylo-Forte Eye Drops (0.2% sodium hyaluronate)
Optive Fusion UD/Preservative-Free Lubricant Eye Drops
Refresh Tears Preservative-Free
Teargain PF Eye Drops

Important: Never switch medicines without consulting your doctor or pharmacist. Even medicines with the same composition may have different inactive ingredients that affect how they work for you.

Understanding the Composition

Systane Hydration Pf contains Sodium hyaluronate 0.15% w/v (Preservative-free lubricant eye drops). Substitute medicines with the same active ingredient work by the same mechanism and treat the same conditions.

Price differences between brands are common and do not indicate a difference in quality or effectiveness. All medicines sold in India must meet the standards set by CDSCO (Central Drugs Standard Control Organisation).

Systane Hydration Pf: At a Glance

Composition: Sodium hyaluronate 0.15% w/v (Preservative-free lubricant eye drops)
Price: ₹760
Prescription: Not required (OTC)
Manufacturer: ALCON INDIA
Known substitutes: 5

Systane Hydration Pf: Substitute FAQs

Are substitutes as effective as the original medicine?

Substitutes with the same active ingredient (salt) work in a similar way. However, inactive ingredients may differ. Always consult your doctor before switching.

Why are some substitutes cheaper?

Generic medicines are usually cheaper because manufacturers don't have the same development costs as the original brand. They contain the same active ingredient in the same strength.

Can I switch to a substitute on my own?

No. Always consult your doctor or pharmacist before switching medicines, even if the substitute has the same composition.

What is the difference between generic and branded medicines?

Generic medicines contain the same active ingredients as branded ones but are sold under different names, often at lower prices. Both are regulated for safety and efficacy.